C₅₃H₉₀O₉Si₃

Base Information

• Chemical Name: C₅₃H₉₀O₉Si₃
• CAS No.: 440643-10-7
• Molecular Formula: C₅₃H₉₀O₉Si₃
• Molecular Weight: 955.549
• Mol file: 440643-10-7.mol

Synonyms:C₅₃H₉₀O₉Si₃

Chemical Property of C₅₃H₉₀O₉Si₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₅₃H₉₀O₉Si₃

There total 18 articles about C₅₃H₉₀O₉Si₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

triisopropylsilyl trifluoromethanesulfonate (80522-42-5) → C53H90O9Si3 (440643-10-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 99 percent / pyridine; DMAP / 15 h

2: aq. LiOH / tetrahydrofuran; 2-methyl-propan-2-ol / 2 h / 20 °C

With pyridine; dmap; lithium hydroxide; In tetrahydrofuran; tert-butyl alcohol;

DOI:10.1016/S0040-4020(02)00050-9

Reference yield:

(5S,6E)-5-methyl-2-[(1R,2E)-1-methyl-5-(benzyloxy)-2-pentenyl]-3-oxo-9-(benzyloxy)-6-nonenoic acid ethyl ester (214484-04-5) → C53H90O9Si3 (440643-10-7)

Guidance literature:

Multi-step reaction with 14 steps

1.1: 96 percent / aq. LiCl / dimethylsulfoxide / 0.67 h / 190 °C

2.1: AD-mix-α / 2-methyl-propan-2-ol; H2O / 24 h / 0 °C

3.1: CSA / benzene; methanol / 32 h

3.2: H₂ / Pd(OH)2 / ethanol / 12 h / 20 °C / 760 Torr

4.1: 98 percent / TFA / methanol / 0.83 h / Heating

5.1: 75 percent / NMO; 4 Angstroem molecular sieves; TPAP / 2-methyl-propan-2-ol; acetonitrile / 20 °C

6.1: pyridine / tetrahydrofuran; toluene / 0.75 h / -78 - 20 °C

6.2: 9-BBN / tetrahydrofuran; toluene / 0.5 h / 20 °C

6.3: 40 percent / NaBO₃*4H₂O / tetrahydrofuran; toluene / 2 h

7.1: Dess-Martin periodinane reagent / CH₂Cl₂ / 2.5 h / 20 °C

8.1: 77 percent / TiCl₄ / CH₂Cl₂ / 0.33 h / -78 °C

9.1: 91 percent / pyridine; DMAP / 27 h / 20 °C

10.1: 99 percent / IBr / toluene; CH₂Cl₂ / 3 h / -80 °C

11.1: 90 percent / aq. LiOH / 1,2-dimethoxy-ethane / 13 h / 60 °C

12.1: 90 percent / pyridine; DMAP / CH₂Cl₂ / 16 h / 20 °C

13.1: 99 percent / pyridine; DMAP / 15 h

14.1: aq. LiOH / tetrahydrofuran; 2-methyl-propan-2-ol / 2 h / 20 °C

With pyridine; dmap; lithium hydroxide; AD-mix-α; N-methyl-2-indolinone; tetrapropylammonium perruthennate; 4 A molecular sieve; camphor-10-sulfonic acid; iodine(I) bromide; titanium tetrachloride; Dess-Martin periodane; trifluoroacetic acid; lithium chloride; In tetrahydrofuran; methanol; 1,2-dimethoxyethane; dichloromethane; water; dimethyl sulfoxide; toluene; acetonitrile; tert-butyl alcohol; benzene;

DOI:10.1016/S0040-4020(02)00050-9

Reference yield:

(3S,4S,5S,9S,10S,11S)-1,13-bis(benzyloxy)-5,9-dimethyl-3,4,10,11-tetrahydroxytridecane-7-one (440643-05-0) → C53H90O9Si3 (440643-10-7)

Guidance literature:

Multi-step reaction with 12 steps

1.1: CSA / benzene; methanol / 32 h

1.2: H₂ / Pd(OH)2 / ethanol / 12 h / 20 °C / 760 Torr

2.1: 98 percent / TFA / methanol / 0.83 h / Heating

3.1: 75 percent / NMO; 4 Angstroem molecular sieves; TPAP / 2-methyl-propan-2-ol; acetonitrile / 20 °C

4.1: pyridine / tetrahydrofuran; toluene / 0.75 h / -78 - 20 °C

4.2: 9-BBN / tetrahydrofuran; toluene / 0.5 h / 20 °C

4.3: 40 percent / NaBO₃*4H₂O / tetrahydrofuran; toluene / 2 h

5.1: Dess-Martin periodinane reagent / CH₂Cl₂ / 2.5 h / 20 °C

6.1: 77 percent / TiCl₄ / CH₂Cl₂ / 0.33 h / -78 °C

7.1: 91 percent / pyridine; DMAP / 27 h / 20 °C

8.1: 99 percent / IBr / toluene; CH₂Cl₂ / 3 h / -80 °C

9.1: 90 percent / aq. LiOH / 1,2-dimethoxy-ethane / 13 h / 60 °C

10.1: 90 percent / pyridine; DMAP / CH₂Cl₂ / 16 h / 20 °C

11.1: 99 percent / pyridine; DMAP / 15 h

12.1: aq. LiOH / tetrahydrofuran; 2-methyl-propan-2-ol / 2 h / 20 °C

With pyridine; dmap; lithium hydroxide; N-methyl-2-indolinone; tetrapropylammonium perruthennate; 4 A molecular sieve; camphor-10-sulfonic acid; iodine(I) bromide; titanium tetrachloride; Dess-Martin periodane; trifluoroacetic acid; In tetrahydrofuran; methanol; 1,2-dimethoxyethane; dichloromethane; toluene; acetonitrile; tert-butyl alcohol; benzene;

DOI:10.1016/S0040-4020(02)00050-9

upstream raw materials:

C₅₃H₈₈O₈Si₃

triisopropylsilyl trifluoromethanesulfonate

(S,E)-1-(benzyloxy)hex-4-en-3-ol

(3S)-1-benzyloxy-4-hexyn-3-ol

Downstream raw materials:

C₅₄H₉₂O₉Si₃

C₆₂H₁₀₀O₁₀Si₃