2-(5-Bromothiophen-2-yl)quinoxaline

Base Information

Chemical Name:2-(5-Bromothiophen-2-yl)quinoxaline
CAS No.:175135-75-8
Molecular Formula:C₁₂H₇BrN₂S
Molecular Weight:291.171
Hs Code.:2934999090
DSSTox Substance ID:DTXSID70384208
Wikidata:Q82176178
Mol file:175135-75-8.mol

Synonyms:2-(5-bromothiophen-2-yl)quinoxaline;175135-75-8;2-(5-bromo-2-thienyl)quinoxaline;Maybridge4_000126;SCHEMBL7865783;DTXSID70384208;HMS1521F16;CCG-46822;IDI1_030708;SR-01000636494-1;BRD-K84921770-001-01-7

Suppliers and Price of 2-(5-Bromothiophen-2-yl)quinoxaline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 2-(5-Bromothiophen-2-yl)quinoxaline

Chemical Property:

Boiling Point:390.1±37.0 °C(Predicted)
PKA:-0.28±0.30(Predicted)
PSA：54.02000
Density:1.609±0.06 g/cm3(Predicted)
LogP:4.12080
XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:289.95133
Heavy Atom Count:16
Complexity:251

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)N=CC(=N2)C3=CC=C(S3)Br

Technology Process of 2-(5-Bromothiophen-2-yl)quinoxaline

There total 3 articles about 2-(5-Bromothiophen-2-yl)quinoxaline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 40353-41-1
2-(thiophen-2-yl)quinoxaline

: 175135-75-8
2-(5-bromothiophen-2-yl)quinoxaline

Guidance literature:: With N-Bromosuccinimide; In N,N-dimethyl-formamide; at 20 ℃;
DOI:10.1016/j.dyepig.2020.108344

Reference yield: 68.0%

: 10531-44-9
2-(2-bromoacetyl)-5-bromothiophene

: 95-54-5
1,2-diamino-benzene

: 175135-75-8
2-(5-bromothiophen-2-yl)quinoxaline

Guidance literature:: In ethanol; for 12h; Reflux;
DOI:10.1002/jhet.4122

Reference yield:

: 1448-87-9
2-chloroquinoxaline

: 175135-75-8
2-(5-bromothiophen-2-yl)quinoxaline

Guidance literature:: Multi-step reaction with 2 steps

1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium phosphate / 1,4-dioxane / 0.5 h / 160 °C / Microwave irradiation

2: N-Bromosuccinimide / N,N-dimethyl-formamide / 20 °C

With potassium phosphate; N-Bromosuccinimide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; N,N-dimethyl-formamide; 1: |Suzuki Coupling;
DOI:10.1016/j.dyepig.2020.108344