methyl 3,4-dioxo-4-phenyl-2-triphenylphosphoranylidenebutanoate

Base Information

• Chemical Name: methyl 3,4-dioxo-4-phenyl-2-triphenylphosphoranylidenebutanoate
• CAS No.: 144823-67-6
• Molecular Formula: C₂₉H₂₃O₄P
• Molecular Weight: 466.473
• Mol file: 144823-67-6.mol

Synonyms:methyl 3,4-dioxo-4-phenyl-2-triphenylphosphoranylidenebutanoate

Chemical Property of methyl 3,4-dioxo-4-phenyl-2-triphenylphosphoranylidenebutanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 3,4-dioxo-4-phenyl-2-triphenylphosphoranylidenebutanoate

There total 2 articles about methyl 3,4-dioxo-4-phenyl-2-triphenylphosphoranylidenebutanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

phenylglyoxylyl chloride (25726-04-9) + methyl (triphenylphosphoranylidene)acetate (21204-67-1,2605-67-6) → methyl 3,4-dioxo-4-phenyl-2-triphenylphosphoranylidenebutanoate (144823-67-6)

Guidance literature:

With triethylamine; In toluene; for 3h; Ambient temperature;

DOI:10.1039/P19940002467

Reference yield:

sodium benzoylformate (43165-51-1) → methyl 3,4-dioxo-4-phenyl-2-triphenylphosphoranylidenebutanoate (144823-67-6)

Guidance literature:

Multi-step reaction with 2 steps

1: oxalyl chloride / diethyl ether

2: 68 percent / Et₃N / toluene / 3 h / Ambient temperature

With oxalyl dichloride; triethylamine; In diethyl ether; toluene;

DOI:10.1039/P19940002467

Reference yield: 67.0%

methyl 3,4-dioxo-4-phenyl-2-triphenylphosphoranylidenebutanoate (144823-67-6) → methyl 4-oxo-4-phenylbut-2-ynoate (41158-32-1) + Triphenylphosphine oxide (791-28-6)

Guidance literature:

at 500 ℃; for 3.5h; under 0.001 - 0.1 Torr;

DOI:10.1039/P19940002467

upstream raw materials:

phenylglyoxylyl chloride

methyl (triphenylphosphoranylidene)acetate

sodium benzoylformate

Downstream raw materials:

methyl 4-oxo-4-phenylbut-2-ynoate

Triphenylphosphine oxide