(Z)-4-(3,4-dimethoxybenzylidene)-4-(4-methoxybenzyl)-5(4H)-oxazolone

Base Information

• Chemical Name: (Z)-4-(3,4-dimethoxybenzylidene)-4-(4-methoxybenzyl)-5(4H)-oxazolone
• CAS No.: 622787-40-0
• Molecular Formula: C₂₀H₁₉NO₅
• Molecular Weight: 353.375
• Mol file: 622787-40-0.mol

Synonyms:(Z)-4-(3,4-dimethoxybenzylidene)-4-(4-methoxybenzyl)-5(4H)-oxazolone

Chemical Property of (Z)-4-(3,4-dimethoxybenzylidene)-4-(4-methoxybenzyl)-5(4H)-oxazolone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of (Z)-4-(3,4-dimethoxybenzylidene)-4-(4-methoxybenzyl)-5(4H)-oxazolone

There total 1 articles about (Z)-4-(3,4-dimethoxybenzylidene)-4-(4-methoxybenzyl)-5(4H)-oxazolone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 22.0%

3,4-dimethoxy-benzaldehyde (120-14-9) + (2-(4-methoxyphenyl)acetyl)glycine → (Z)-4-(3,4-dimethoxybenzylidene)-4-(4-methoxybenzyl)-5(4H)-oxazolone (622787-40-0)

Guidance literature:

With sodium acetate; acetic anhydride; at 70 - 80 ℃;

DOI:10.3987/COM-06-10710

Reference yield: 80.0%

N-butylamine (109-73-9,85404-21-3) + (Z)-4-(3,4-dimethoxybenzylidene)-4-(4-methoxybenzyl)-5(4H)-oxazolone (622787-40-0) → (Z)-N-butyl-3-(3,4-dimethoxyphenyl)-2-(4-methoxyphenylacetylamino)-2-propenamide (622787-11-5)

Guidance literature:

With triethylamine; In chloroform; for 3h; Heating;

DOI:10.3987/COM-06-10710

Reference yield:

(Z)-4-(3,4-dimethoxybenzylidene)-4-(4-methoxybenzyl)-5(4H)-oxazolone (622787-40-0) → 3-butylaminocarbonyl-6,7-dimethoxy-1-(4-methoxybenzyl)isoquinoline

Guidance literature:

Multi-step reaction with 2 steps

1: 80 percent / triethylamine / CHCl₃ / 3 h / Heating

2: methanol / 1 h / 20 °C / Irradiation

With triethylamine; In methanol; chloroform;

DOI:10.3987/COM-06-10710

upstream raw materials:

3,4-dimethoxy-benzaldehyde

Downstream raw materials:

(Z)-N-butyl-3-(3,4-dimethoxyphenyl)-2-(4-methoxyphenylacetylamino)-2-propenamide