2,2'-{[(1-benzyl-3,5-dimethyl-1H-pyrazol-4-yl)methanediyl]di(sulfanediyl)}diethanol hydrochloride

Base Information

• Chemical Name: 2,2'-{[(1-benzyl-3,5-dimethyl-1H-pyrazol-4-yl)methanediyl]di(sulfanediyl)}diethanol hydrochloride
• CAS No.: 1303527-00-5
• Molecular Formula: C₁₇H₂₄N₂O₂S₂*ClH
• Molecular Weight: 388.983
• Mol file: 1303527-00-5.mol

Synonyms:2,2'-{[(1-benzyl-3,5-dimethyl-1H-pyrazol-4-yl)methanediyl]di(sulfanediyl)}diethanol hydrochloride

Chemical Property of 2,2'-{[(1-benzyl-3,5-dimethyl-1H-pyrazol-4-yl)methanediyl]di(sulfanediyl)}diethanol hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,2'-{[(1-benzyl-3,5-dimethyl-1H-pyrazol-4-yl)methanediyl]di(sulfanediyl)}diethanol hydrochloride

There total 2 articles about 2,2'-{[(1-benzyl-3,5-dimethyl-1H-pyrazol-4-yl)methanediyl]di(sulfanediyl)}diethanol hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

2-hydroxyethanethiol (60-24-2) + 1-benzyl-3,5-dimethyl-1H-pyrazole-4-carbaldehyde (2644-94-2) → 2,2'-{[(1-benzyl-3,5-dimethyl-1H-pyrazol-4-yl)methanediyl]di(sulfanediyl)}diethanol hydrochloride (1303527-00-5)

Guidance literature:

With chloro-trimethyl-silane; at 20 ℃; for 0.25 - 0.333333h;

DOI:10.1134/S1070428011030286

Reference yield:

2-hydroxyethanethiol (60-24-2) + 1-benzyl-3,5-dimethyl-1H-pyrazole-4-carbaldehyde (2644-94-2) → 2,2'-{[(1-benzyl-3,5-dimethyl-1H-pyrazol-4-yl)methanediyl]di(sulfanediyl)}diethanol hydrochloride (1303527-00-5) + 1-benzyl-3,5-dimethyl-4-(1,3-oxathiolan-2-yl)-1H-pyrazole hydrochloride (1367597-40-7)

Guidance literature:

at 20 - 22 ℃; for 0.25h; Overall yield = 0.53 g;

DOI:10.1007/s10593-012-0927-0

Reference yield: 76.0%

2,2'-{[(1-benzyl-3,5-dimethyl-1H-pyrazol-4-yl)methanediyl]di(sulfanediyl)}diethanol hydrochloride (1303527-00-5) → 2,2'-{[(1-benzyl-3,5-dimethyl-1H-pyrazol-4-yl)methanediyl]di(sulfanediyl)}diethanol (1303644-24-7)

Guidance literature:

With ammonia; In water; at 20 - 22 ℃;

DOI:10.1007/s10593-012-0927-0

upstream raw materials:

2-hydroxyethanethiol

1-benzyl-3,5-dimethyl-1H-pyrazole-4-carbaldehyde

Downstream raw materials:

2,2'-{[(1-benzyl-3,5-dimethyl-1H-pyrazol-4-yl)methanediyl]di(sulfanediyl)}diethanol