2-cyano-3-(2-nitro-phenyl)-acrylic acid p-toluidide

Base Information

• Chemical Name: 2-cyano-3-(2-nitro-phenyl)-acrylic acid p-toluidide
• CAS No.: 121217-52-5
• Molecular Formula: C₁₇H₁₃N₃O₃
• Molecular Weight: 307.309
• Mol file: 121217-52-5.mol

Synonyms:2-cyano-3-(2-nitro-phenyl)-acrylic acid p-toluidide

Chemical Property of 2-cyano-3-(2-nitro-phenyl)-acrylic acid p-toluidide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-cyano-3-(2-nitro-phenyl)-acrylic acid p-toluidide

There total 1 articles about 2-cyano-3-(2-nitro-phenyl)-acrylic acid p-toluidide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

2-cyano-N-(4-methylphenyl)acetamide (6876-54-6) + 2-nitro-benzaldehyde (552-89-6) → 2-cyano-3-(2-nitro-phenyl)-acrylic acid p-toluidide (121217-52-5)

Guidance literature:

With piperidine; In ethanol; for 1h; Heating;

DOI:10.1007/BF00633505

Reference yield: 85.0%

2-cyano-3-(2-nitro-phenyl)-acrylic acid p-toluidide (121217-52-5) → 2-Amino-quinoline-3-carboxylic acid p-tolylamide (121217-61-6)

Guidance literature:

With iron; In acetic acid; for 7h; Heating;

DOI:10.1007/BF00633505

Reference yield:

2-cyano-3-(2-nitro-phenyl)-acrylic acid p-toluidide (121217-52-5) → 2-p-toluidino-quinoline-3-carbonitrile

Guidance literature:

With acetic acid; zinc;

DOI:10.1039/jr9300002739

upstream raw materials:

2-cyano-N-(4-methylphenyl)acetamide

2-nitro-benzaldehyde

Downstream raw materials:

2-Amino-quinoline-3-carboxylic acid p-tolylamide

Refernces