N⁶-phtaloyldeoxyadenosine S,S-diphenyl 3'-phosphorodithioate

Base Information

• Chemical Name: N⁶-phtaloyldeoxyadenosine S,S-diphenyl 3'-phosphorodithioate
• CAS No.: 84765-90-2
• Molecular Formula: C₃₀H₂₄N₅O₆PS₂
• Molecular Weight: 645.656
• Mol file: 84765-90-2.mol

Synonyms:N⁶-phtaloyldeoxyadenosine S,S-diphenyl 3'-phosphorodithioate

Chemical Property of N⁶-phtaloyldeoxyadenosine S,S-diphenyl 3'-phosphorodithioate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N⁶-phtaloyldeoxyadenosine S,S-diphenyl 3'-phosphorodithioate

There total 1 articles about N⁶-phtaloyldeoxyadenosine S,S-diphenyl 3'-phosphorodithioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

Dithiophosphoric acid O-{(2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-[6-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-purin-9-yl]-tetrahydro-furan-3-yl} ester S,S'-diphenyl ester (84780-17-6) → N6-phtaloyldeoxyadenosine S,S-diphenyl 3'-phosphorodithioate (84765-90-2)

Guidance literature:

With trifluoroacetic acid; In chloroform; for 0.0833333h; Ambient temperature;

DOI:10.1016/S0040-4039(00)85601-4

Reference yield: 89.0%

N6-phtaloyldeoxyadenosine S,S-diphenyl 3'-phosphorodithioate (84765-90-2) + triethylammonium S-phenyl 5'-O-dimethoxytrityl-N6-phthaloyldeoxyadenosine 3'-phosphorothioate (84765-93-5) → C75H60N10O14P2S3 (84780-20-1)

Guidance literature:

With MDS, NT; for 0.5h;

DOI:10.1016/S0040-4039(00)85601-4

upstream raw materials:

Dithiophosphoric acid O-{(2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-[6-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-purin-9-yl]-tetrahydro-furan-3-yl} ester S,S'-diphenyl ester

Downstream raw materials:

C₇₅H₆₀N₁₀O₁₄P₂S₃