(-)-(6S,10S)-5-methyl-8-(1'-ethyl-2'-pentenyl)-9-<(hydroxyimino)methyl>-12-benzyl-6,7,8,9,10,11-hexahydro-6,10-imino-5H-cyclooctindole

Base Information

• Chemical Name: (-)-(6S,10S)-5-methyl-8-(1'-ethyl-2'-pentenyl)-9-<(hydroxyimino)methyl>-12-benzyl-6,7,8,9,10,11-hexahydro-6,10-imino-5H-cyclooctindole
• CAS No.: 143065-01-4
• Molecular Formula: C₃₀H₃₇N₃O
• Molecular Weight: 455.643
• Mol file: 143065-01-4.mol

Synonyms:(-)-(6S,10S)-5-methyl-8-(1'-ethyl-2'-pentenyl)-9-<(hydroxyimino)methyl>-12-benzyl-6,7,8,9,10,11-hexahydro-6,10-imino-5H-cyclooctindole

Chemical Property of (-)-(6S,10S)-5-methyl-8-(1'-ethyl-2'-pentenyl)-9-<(hydroxyimino)methyl>-12-benzyl-6,7,8,9,10,11-hexahydro-6,10-imino-5H-cyclooctindole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (-)-(6S,10S)-5-methyl-8-(1'-ethyl-2'-pentenyl)-9-<(hydroxyimino)methyl>-12-benzyl-6,7,8,9,10,11-hexahydro-6,10-imino-5H-cyclooctindole

There total 1 articles about (-)-(6S,10S)-5-methyl-8-(1'-ethyl-2'-pentenyl)-9-<(hydroxyimino)methyl>-12-benzyl-6,7,8,9,10,11-hexahydro-6,10-imino-5H-cyclooctindole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

(-)-(6S,10S)-5-methyl-8-(1'-ethyl-2'-pentenyl)-12-benzyl-6,7,8,9,10,11-hexahydro-6,10-imino-5H-cyclooctindole-9-carboxaldehyde (143065-00-3,143120-76-7,143167-04-8) → (-)-(6S,10S)-5-methyl-8-(1'-ethyl-2'-pentenyl)-9-<(hydroxyimino)methyl>-12-benzyl-6,7,8,9,10,11-hexahydro-6,10-imino-5H-cyclooctindole (143065-01-4)

Guidance literature:

With hydroxylamine hydrochloride; In ethanol; for 3h; Heating;

DOI:10.1021/jo00055a019

Reference yield: 80.0%

(-)-(6S,10S)-5-methyl-8-(1'-ethyl-2'-pentenyl)-9-<(hydroxyimino)methyl>-12-benzyl-6,7,8,9,10,11-hexahydro-6,10-imino-5H-cyclooctindole (143065-01-4) → C27H30N2O2 (143076-06-6)

Guidance literature:

With pyridine; sodium periodate; osmium(VIII) oxide; sodium hydrogensulfite; In tetrahydrofuran; methanol; at 0 ℃;

DOI:10.1021/ja00043a043

Reference yield:

(-)-(6S,10S)-5-methyl-8-(1'-ethyl-2'-pentenyl)-9-<(hydroxyimino)methyl>-12-benzyl-6,7,8,9,10,11-hexahydro-6,10-imino-5H-cyclooctindole (143065-01-4) → (-)-Nb-benzylsuaveoline (143120-75-6)

Guidance literature:

Multi-step reaction with 2 steps

2: 70 percent / hydroxylamine hydrochloride / ethanol / 21 h / Heating

With hydroxylamine hydrochloride; In ethanol;

DOI:10.1021/jo00055a019

upstream raw materials:

(-)-(6S,10S)-5-methyl-8-(1'-ethyl-2'-pentenyl)-12-benzyl-6,7,8,9,10,11-hexahydro-6,10-imino-5H-cyclooctindole-9-carboxaldehyde

Downstream raw materials:

C₂₇H₃₀N₂O₂

(-)-N_b-benzylsuaveoline