ethyl 2-(4-isopropylphenoxy)-3-[4-[2-[(4-(pyridin-2-yl)benzoyl)amino]ethoxy]phenyl]propionate

Base Information

Chemical Name:ethyl 2-(4-isopropylphenoxy)-3-[4-[2-[(4-(pyridin-2-yl)benzoyl)amino]ethoxy]phenyl]propionate
CAS No.:223119-79-7
Molecular Formula:C₃₄H₃₆N₂O₅
Molecular Weight:552.67
Hs Code.:

Synonyms:ethyl 2-(4-isopropylphenoxy)-3-[4-[2-[(4-(pyridin-2-yl)benzoyl)amino]ethoxy]phenyl]propionate

Suppliers and Price of ethyl 2-(4-isopropylphenoxy)-3-[4-[2-[(4-(pyridin-2-yl)benzoyl)amino]ethoxy]phenyl]propionate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of ethyl 2-(4-isopropylphenoxy)-3-[4-[2-[(4-(pyridin-2-yl)benzoyl)amino]ethoxy]phenyl]propionate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of ethyl 2-(4-isopropylphenoxy)-3-[4-[2-[(4-(pyridin-2-yl)benzoyl)amino]ethoxy]phenyl]propionate

There total 7 articles about ethyl 2-(4-isopropylphenoxy)-3-[4-[2-[(4-(pyridin-2-yl)benzoyl)amino]ethoxy]phenyl]propionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4385-62-0
4-(pyridin-2-yl)benzoic acid

: 223126-46-3
ethyl 3-[4-(2-aminoethoxy)phenyl]-2-(4-isopropylphenoxy)propionate

: 223119-79-7
ethyl 2-(4-isopropylphenoxy)-3-[4-[2-[(4-(pyridin-2-yl)benzoyl)amino]ethoxy]phenyl]propionate

Guidance literature:: With 1,1'-carbonyldiimidazole;

Reference yield:

: 99-89-8
4-Isopropylphenol

: 223119-79-7
ethyl 2-(4-isopropylphenoxy)-3-[4-[2-[(4-(pyridin-2-yl)benzoyl)amino]ethoxy]phenyl]propionate

Guidance literature:: Multi-step reaction with 5 steps

1: 56 percent / triphenylphosphine; diethyl azodicarboxylate / toluene / 20 °C

2: 99 percent / H₂ / Pd/C / ethanol / 50 °C

3: 99 percent / triphenylphosphine; diethyl azodicarboxylate / toluene / 0 - 20 °C

4: HCl / dioxane / 20 °C

5: triethylamine; diethylphosphoryl cyanide / dimethylformamide

With hydrogenchloride; diethylphosphoryl cyanide; hydrogen; triethylamine; triphenylphosphine; diethylazodicarboxylate; palladium on activated charcoal; In 1,4-dioxane; ethanol; N,N-dimethyl-formamide; toluene; 1: Mitsunobu reaction / 3: Mitsunobu reaction;
DOI:10.1016/j.bmc.2004.01.048

Reference yield:

: 62517-34-4
ethyl 2-hydroxy-3-(4-hydroxyphenyl)propionate

: 223119-79-7
ethyl 2-(4-isopropylphenoxy)-3-[4-[2-[(4-(pyridin-2-yl)benzoyl)amino]ethoxy]phenyl]propionate

Guidance literature:: Multi-step reaction with 6 steps

1: 99 percent / K₂CO₃ / dimethylformamide / 4 h / 60 °C

2: 56 percent / triphenylphosphine; diethyl azodicarboxylate / toluene / 20 °C

3: 99 percent / H₂ / Pd/C / ethanol / 50 °C

4: 99 percent / triphenylphosphine; diethyl azodicarboxylate / toluene / 0 - 20 °C

5: HCl / dioxane / 20 °C

6: triethylamine; diethylphosphoryl cyanide / dimethylformamide

With hydrogenchloride; diethylphosphoryl cyanide; hydrogen; potassium carbonate; triethylamine; triphenylphosphine; diethylazodicarboxylate; palladium on activated charcoal; In 1,4-dioxane; ethanol; N,N-dimethyl-formamide; toluene; 2: Mitsunobu reaction / 4: Mitsunobu reaction;
DOI:10.1016/j.bmc.2004.01.048