2-Pyridinamine,6-ethynyl-(9CI)

Base Information

Chemical Name:2-Pyridinamine,6-ethynyl-(9CI)
CAS No.:173314-98-2
Molecular Formula:C7H6 N2
Molecular Weight:118.138
Hs Code.:
Mol file:173314-98-2.mol

Synonyms:6-Ethynyl-2-pyridinamine

Suppliers and Price of 2-Pyridinamine,6-ethynyl-(9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-Ethynyl-2-pyridinamine
100mg
$ 240.00

TRC
6-Ethynyl-2-pyridinamine
10mg
$ 45.00

Alichem
6-Ethynylpyridin-2-amine
10g
$ 2320.64

Alichem
6-Ethynylpyridin-2-amine
25g
$ 4835.25

Alichem
6-Ethynylpyridin-2-amine
5g
$ 1650.32

AK Scientific
6-Ethynylpyridin-2-amine
2.5g
$ 1459.00

Activate Scientific
6-Ethynyl-2-pyridinamine 95+%
250 mg
$ 244.00

Activate Scientific
6-Ethynyl-2-pyridinamine 95+%
1 g
$ 509.00

Acrotein
6-Ethynyl-2-pyridinamine 97%
1g
$ 363.00

Acrotein
6-Ethynyl-2-pyridinamine 97%
0.25g
$ 161.33

Total 8 raw suppliers

Chemical Property of 2-Pyridinamine,6-ethynyl-(9CI)

Chemical Property:

PSA：38.91000
LogP:1.22630
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C

Purity/Quality:

97% ^*data from raw suppliers

6-Ethynyl-2-pyridinamine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-Pyridinamine,6-ethynyl-(9CI)

There total 4 articles about 2-Pyridinamine,6-ethynyl-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 173314-97-1
2-amino-6-<(trimethylsilyl)ethynyl>pyridine

: 173314-98-2
6-ethynyl-pyridin-2-ylamine

Guidance literature:: With potassium hydroxide; In methanol; for 1h;
DOI:10.1021/jo3016659

Reference yield: 67.0%

: 19798-81-3,1184170-10-2
2-Amino-6-bromopyridine

: 1066-54-2
trimethylsilylacetylene

: 173314-98-2
6-ethynyl-pyridin-2-ylamine

Guidance literature:: 2-Amino-6-bromopyridine; trimethylsilylacetylene; With copper(l) iodide; triethylamine; bis-triphenylphosphine-palladium(II) chloride; In benzene; at 50 ℃; for 7h; Inert atmosphere;

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at -20 - 0 ℃;

Reference yield:

: 19798-81-3,1184170-10-2
2-Amino-6-bromopyridine

: 173314-98-2
6-ethynyl-pyridin-2-ylamine

Guidance literature:: Multi-step reaction with 2 steps

1: 93 percent / Et₂NH, (PPh₃)2PdCl₂, CuI / 10 h / Ambient temperature

2: 91 percent / H₂O, n-Bu₄F / tetrahydrofuran / 4 h / 0 °C

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; water; diethylamine; In tetrahydrofuran;
DOI:10.1021/ja00155a006