Technology Process of C45H58N12O10
There total 6 articles about C45H58N12O10 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
BOC-O-benzyl-L-serine;
With
benzotriazol-1-ol; dicyclohexyl-carbodiimide;
In
dichloromethane;
at 20 ℃;
for 12h;
C30H39N11O6;
In
dichloromethane; N,N-dimethyl-formamide;
at 20 ℃;
for 24h;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: HOBt; DCC / CH2Cl2; dimethylsulfoxide / 12 h
1.2: 74 percent / CH2Cl2; dimethylsulfoxide / 24 h
2.1: H2 / Pd/C / methanol / 12 h / 20 °C
3.1: HOBt; DCC / dimethylformamide / 8 h / 20 °C
3.2: 73 percent / methanol; dimethylformamide / 12 h / 20 °C
4.1: aq. trifluoroacetic acid / 8 h / 20 °C
5.1: HOBt; DCC / CH2Cl2 / 12 h / 20 °C
5.2: 80 percent / CH2Cl2; dimethylformamide / 24 h / 20 °C
With
hydrogen; benzotriazol-1-ol; dicyclohexyl-carbodiimide; trifluoroacetic acid;
palladium on activated charcoal;
In
methanol; dichloromethane; dimethyl sulfoxide; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: HOBt; DCC / CH2Cl2; dimethylsulfoxide / 12 h
1.2: 74 percent / CH2Cl2; dimethylsulfoxide / 24 h
2.1: H2 / Pd/C / methanol / 12 h / 20 °C
3.1: HOBt; DCC / dimethylformamide / 8 h / 20 °C
3.2: 73 percent / methanol; dimethylformamide / 12 h / 20 °C
4.1: aq. trifluoroacetic acid / 8 h / 20 °C
5.1: HOBt; DCC / CH2Cl2 / 12 h / 20 °C
5.2: 80 percent / CH2Cl2; dimethylformamide / 24 h / 20 °C
With
hydrogen; benzotriazol-1-ol; dicyclohexyl-carbodiimide; trifluoroacetic acid;
palladium on activated charcoal;
In
methanol; dichloromethane; dimethyl sulfoxide; N,N-dimethyl-formamide;
