(4aS,8aR)-5-[2-(1,3-dioxolan-2-yl)ethyl]-1-[(1R)-2-hydroxy-1-phenylethyl]-1,2,3,4,4a,7,8,8a-octahydroquinoline

Base Information

Chemical Name:(4aS,8aR)-5-[2-(1,3-dioxolan-2-yl)ethyl]-1-[(1R)-2-hydroxy-1-phenylethyl]-1,2,3,4,4a,7,8,8a-octahydroquinoline
CAS No.:1106986-52-0
Molecular Formula:C₂₂H₃₁NO₃
Molecular Weight:357.493
Hs Code.:

Synonyms:(4aS,8aR)-5-[2-(1,3-dioxolan-2-yl)ethyl]-1-[(1R)-2-hydroxy-1-phenylethyl]-1,2,3,4,4a,7,8,8a-octahydroquinoline

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (4aS,8aR)-5-[2-(1,3-dioxolan-2-yl)ethyl]-1-[(1R)-2-hydroxy-1-phenylethyl]-1,2,3,4,4a,7,8,8a-octahydroquinoline

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Technology Process of (4aS,8aR)-5-[2-(1,3-dioxolan-2-yl)ethyl]-1-[(1R)-2-hydroxy-1-phenylethyl]-1,2,3,4,4a,7,8,8a-octahydroquinoline

There total 1 articles about (4aS,8aR)-5-[2-(1,3-dioxolan-2-yl)ethyl]-1-[(1R)-2-hydroxy-1-phenylethyl]-1,2,3,4,4a,7,8,8a-octahydroquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 1106986-32-6
(3R,7aS,11aS)-8-[2-(1,3-dioxolan-2-yl)ethyl]-5-oxo-3-phenyl-2,3,5,6,7,7a,10,11-octahydrooxazolo[2,3-j]quinoline

: 1106986-52-0
(4aS,8aR)-5-[2-(1,3-dioxolan-2-yl)ethyl]-1-[(1R)-2-hydroxy-1-phenylethyl]-1,2,3,4,4a,7,8,8a-octahydroquinoline

: 5-[2-(1,3-dioxolan-2-yl)ethyl]-1-[2-hydroxy-1-phenylethyl]-1,2,3,4,4a,7,8,8a-octahydroquinoline

Guidance literature:: With aluminum (III) chloride; lithium aluminium tetrahydride; In tetrahydrofuran; at -78 - 25 ℃; for 3h; Inert atmosphere;
DOI:10.1021/jo802587h