tert-butyl 3-(4-(1-(3'-ethyl-6-fluorobiphenyl-2-yl)-1-hydroxy-5-methoxypentyl)piperidine-1-carbonyl)benzylcarbamate

Base Information

Chemical Name:tert-butyl 3-(4-(1-(3'-ethyl-6-fluorobiphenyl-2-yl)-1-hydroxy-5-methoxypentyl)piperidine-1-carbonyl)benzylcarbamate
CAS No.:952709-15-8
Molecular Formula:C₃₈H₄₉FN₂O₅
Molecular Weight:632.816
Hs Code.:

Synonyms:tert-butyl 3-(4-(1-(3'-ethyl-6-fluorobiphenyl-2-yl)-1-hydroxy-5-methoxypentyl)piperidine-1-carbonyl)benzylcarbamate

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Chemical Property of tert-butyl 3-(4-(1-(3'-ethyl-6-fluorobiphenyl-2-yl)-1-hydroxy-5-methoxypentyl)piperidine-1-carbonyl)benzylcarbamate

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Technology Process of tert-butyl 3-(4-(1-(3'-ethyl-6-fluorobiphenyl-2-yl)-1-hydroxy-5-methoxypentyl)piperidine-1-carbonyl)benzylcarbamate

There total 1 articles about tert-butyl 3-(4-(1-(3'-ethyl-6-fluorobiphenyl-2-yl)-1-hydroxy-5-methoxypentyl)piperidine-1-carbonyl)benzylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

: 952708-96-2
1-(3'-ethyl-6-fluorobiphenyl-2-yl)-5-methoxy-1-(piperidin-4-yl)pentan-1-ol

: 117445-22-4
3-(tert-butoxycarbonylamino-methyl)benzoic acid

: 952709-15-8
tert-butyl 3-(4-(1-(3'-ethyl-6-fluorobiphenyl-2-yl)-1-hydroxy-5-methoxypentyl)piperidine-1-carbonyl)benzylcarbamate

Guidance literature:: With benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 25 ℃; for 20h;

Reference yield: 100.0%

: 952709-15-8
tert-butyl 3-(4-(1-(3'-ethyl-6-fluorobiphenyl-2-yl)-1-hydroxy-5-methoxypentyl)piperidine-1-carbonyl)benzylcarbamate

: 952706-99-9
(3-(aminomethyl)phenyl)(4-(1-(3'-ethyl-6-fluorobiphenyl-2-yl)-1-hydroxy-5-methoxypentyl)piperidin-1-yl)methanone

Guidance literature:: tert-butyl 3-(4-(1-(3'-ethyl-6-fluorobiphenyl-2-yl)-1-hydroxy-5-methoxypentyl)piperidine-1-carbonyl)benzylcarbamate; With hydrogenchloride; water; In acetonitrile; at 25 ℃; for 24h;

pH=14;