((1S,2S,3R,4R)-2-(3-hydroxybenzyl)-4-(tert-butyldimethylsilyloxy)-3-((3S,1E)-3-(tert-butyldimethylsilyloxy)oct-1-enyl)cyclopentyl)methyl 4-methylbenzenesulfonate

Base Information

Chemical Name:((1S,2S,3R,4R)-2-(3-hydroxybenzyl)-4-(tert-butyldimethylsilyloxy)-3-((3S,1E)-3-(tert-butyldimethylsilyloxy)oct-1-enyl)cyclopentyl)methyl 4-methylbenzenesulfonate
CAS No.:1425937-50-3
Molecular Formula:C₄₀H₆₆O₆SSi₂
Molecular Weight:731.197
Hs Code.:

((1S,2S,3R,4R)-2-(3-hydroxybenzyl)-4-(tert-butyldimethylsilyloxy)-3-((3S,1E)-3-(tert-butyldimethylsilyloxy)oct-1-enyl)cyclopentyl)methyl 4-methylbenzenesulfonate

Synonyms:((1S,2S,3R,4R)-2-(3-hydroxybenzyl)-4-(tert-butyldimethylsilyloxy)-3-((3S,1E)-3-(tert-butyldimethylsilyloxy)oct-1-enyl)cyclopentyl)methyl 4-methylbenzenesulfonate

Suppliers and Price of ((1S,2S,3R,4R)-2-(3-hydroxybenzyl)-4-(tert-butyldimethylsilyloxy)-3-((3S,1E)-3-(tert-butyldimethylsilyloxy)oct-1-enyl)cyclopentyl)methyl 4-methylbenzenesulfonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of ((1S,2S,3R,4R)-2-(3-hydroxybenzyl)-4-(tert-butyldimethylsilyloxy)-3-((3S,1E)-3-(tert-butyldimethylsilyloxy)oct-1-enyl)cyclopentyl)methyl 4-methylbenzenesulfonate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of ((1S,2S,3R,4R)-2-(3-hydroxybenzyl)-4-(tert-butyldimethylsilyloxy)-3-((3S,1E)-3-(tert-butyldimethylsilyloxy)oct-1-enyl)cyclopentyl)methyl 4-methylbenzenesulfonate

There total 10 articles about ((1S,2S,3R,4R)-2-(3-hydroxybenzyl)-4-(tert-butyldimethylsilyloxy)-3-((3S,1E)-3-(tert-butyldimethylsilyloxy)oct-1-enyl)cyclopentyl)methyl 4-methylbenzenesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 1425937-47-8
((1S,2S,3R,4R)-2-(3-(benzyloxy)benzyl)-4-(tert-butyldimethylsilyloxy)-3-((3S,1E)-3-(tert-butyldimethylsilyloxy)oct-1-enyl)cyclopentyl)methyl 4-methylbenzenesulfonate

: 1425937-50-3
((1S,2S,3R,4R)-2-(3-hydroxybenzyl)-4-(tert-butyldimethylsilyloxy)-3-((3S,1E)-3-(tert-butyldimethylsilyloxy)oct-1-enyl)cyclopentyl)methyl 4-methylbenzenesulfonate

Guidance literature:: With 5%-palladium/activated carbon; hydrogen; potassium hydroxide; In methanol; for 5h;

Reference yield:

: 1425937-59-2
(3R)-1-[3-(benzyloxy)benzyl]-5-oxo-3-(triethylsilyloxy)cyclopent-1-ene

: 1425937-50-3
((1S,2S,3R,4R)-2-(3-hydroxybenzyl)-4-(tert-butyldimethylsilyloxy)-3-((3S,1E)-3-(tert-butyldimethylsilyloxy)oct-1-enyl)cyclopentyl)methyl 4-methylbenzenesulfonate

Guidance literature:: Multi-step reaction with 6 steps

1.1: n-butyllithium; copper(l) cyanide; methyllithium / diethyl ether; hexane; tetrahydrofuran / 0.5 h / -70 °C

1.2: 0.5 h / -70 °C

2.1: toluene-4-sulfonic acid / tetrahydrofuran; dichloromethane / 1.5 h / 25 °C / Cooling with ice

2.2: 1 h / 20 °C

3.1: 1H-imidazole / ethyl acetate / 20 °C

4.1: 9-bora-bicyclo[3.3.1]nonane / tetrahydrofuran / 0 °C / Inert atmosphere

4.2: 1.75 h / 0 - 20 °C

5.1: triethylamine / dichloromethane / 0 °C / Inert atmosphere

6.1: hydrogen; potassium hydroxide; 5%-palladium/activated carbon / methanol / 5 h

With 1H-imidazole; n-butyllithium; 5%-palladium/activated carbon; methyllithium; hydrogen; copper(l) cyanide; toluene-4-sulfonic acid; triethylamine; 9-bora-bicyclo[3.3.1]nonane; potassium hydroxide; In tetrahydrofuran; methanol; diethyl ether; hexane; dichloromethane; ethyl acetate;

Reference yield:

: 183073-00-9
(1S,2E)-1-pentyl-3-(1,1,1-tributylstannyl)-2-propenyl (1,1,1-triethylsilyl) ether

: 1425937-50-3
((1S,2S,3R,4R)-2-(3-hydroxybenzyl)-4-(tert-butyldimethylsilyloxy)-3-((3S,1E)-3-(tert-butyldimethylsilyloxy)oct-1-enyl)cyclopentyl)methyl 4-methylbenzenesulfonate

Guidance literature:: Multi-step reaction with 6 steps

1.1: n-butyllithium; copper(l) cyanide; methyllithium / diethyl ether; hexane; tetrahydrofuran / 0.5 h / -70 °C

1.2: 0.5 h / -70 °C

2.1: toluene-4-sulfonic acid / tetrahydrofuran; dichloromethane / 1.5 h / 25 °C / Cooling with ice

2.2: 1 h / 20 °C

3.1: 1H-imidazole / ethyl acetate / 20 °C

4.1: 9-bora-bicyclo[3.3.1]nonane / tetrahydrofuran / 0 °C / Inert atmosphere

4.2: 1.75 h / 0 - 20 °C

5.1: triethylamine / dichloromethane / 0 °C / Inert atmosphere

6.1: hydrogen; potassium hydroxide; 5%-palladium/activated carbon / methanol / 5 h

With 1H-imidazole; n-butyllithium; 5%-palladium/activated carbon; methyllithium; hydrogen; copper(l) cyanide; toluene-4-sulfonic acid; triethylamine; 9-bora-bicyclo[3.3.1]nonane; potassium hydroxide; In tetrahydrofuran; methanol; diethyl ether; hexane; dichloromethane; ethyl acetate;