(E)-3-Phenyl-N-[3-(4-{3-[(E)-(3-phenyl-acryloyl)amino]-propylamino}-butylamino)-propyl]-acrylamide

Base Information

Chemical Name:(E)-3-Phenyl-N-[3-(4-{3-[(E)-(3-phenyl-acryloyl)amino]-propylamino}-butylamino)-propyl]-acrylamide
CAS No.:191990-79-1
Molecular Formula:C₂₈H₃₈N₄O₂
Molecular Weight:462.635
Hs Code.:

Synonyms:(E)-3-Phenyl-N-[3-(4-{3-[(E)-(3-phenyl-acryloyl)amino]-propylamino}-butylamino)-propyl]-acrylamide

Suppliers and Price of (E)-3-Phenyl-N-[3-(4-{3-[(E)-(3-phenyl-acryloyl)amino]-propylamino}-butylamino)-propyl]-acrylamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (E)-3-Phenyl-N-[3-(4-{3-[(E)-(3-phenyl-acryloyl)amino]-propylamino}-butylamino)-propyl]-acrylamide

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Technology Process of (E)-3-Phenyl-N-[3-(4-{3-[(E)-(3-phenyl-acryloyl)amino]-propylamino}-butylamino)-propyl]-acrylamide

There total 5 articles about (E)-3-Phenyl-N-[3-(4-{3-[(E)-(3-phenyl-acryloyl)amino]-propylamino}-butylamino)-propyl]-acrylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: (E)-N-(3-Amino-propyl)-N-(4-{(3-amino-propyl)-[(E)-(3-phenyl-acryloyl)]-amino}-butyl)-3-phenyl-acrylamide; hydrochloride

: 191990-79-1
(E)-3-Phenyl-N-[3-(4-{3-[(E)-(3-phenyl-acryloyl)amino]-propylamino}-butylamino)-propyl]-acrylamide

Guidance literature:: With potassium tert-butylate; In toluene; for 4h; Heating;
DOI:10.1002/hlca.19970800328

Reference yield: 80.0%

: 23776-87-6
2,5‐dioxopyrrolidin‐1‐yl cinnamate

: 71-44-3
Spermine

: 191990-79-1
(E)-3-Phenyl-N-[3-(4-{3-[(E)-(3-phenyl-acryloyl)amino]-propylamino}-butylamino)-propyl]-acrylamide

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 ℃;
DOI:10.1246/Cl.2005.264

Reference yield:

: 140-10-3
(E)-3-phenylacrylic acid

: 191990-79-1
(E)-3-Phenyl-N-[3-(4-{3-[(E)-(3-phenyl-acryloyl)amino]-propylamino}-butylamino)-propyl]-acrylamide

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / N,N'-dicyclohexylcarbodiimide / tetrahydrofuran; dimethylformamide / 13 h / 0 - 25 °C

2: 80 percent / iPr₂NEt / CH₂Cl₂ / 0 °C

With N-ethyl-N,N-diisopropylamine; dicyclohexyl-carbodiimide; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1246/Cl.2005.264