2-amino-4-chloro-6-di(4-methoxybenzyl)-amino-5-pyrimidine carbaldehyde

Base Information

Chemical Name:2-amino-4-chloro-6-di(4-methoxybenzyl)-amino-5-pyrimidine carbaldehyde
CAS No.:244288-51-5
Molecular Formula:C₂₁H₂₁ClN₄O₃
Molecular Weight:412.876
Hs Code.:

Synonyms:2-amino-4-chloro-6-di(4-methoxybenzyl)-amino-5-pyrimidine carbaldehyde

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Chemical Property of 2-amino-4-chloro-6-di(4-methoxybenzyl)-amino-5-pyrimidine carbaldehyde

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Technology Process of 2-amino-4-chloro-6-di(4-methoxybenzyl)-amino-5-pyrimidine carbaldehyde

There total 1 articles about 2-amino-4-chloro-6-di(4-methoxybenzyl)-amino-5-pyrimidine carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.2%

: 17061-62-0
N,N-bis(p-methoxybenzyl)amine

: 5604-46-6
2-amino-4,6-dichloropyrimidine-5-carboxaldehyde

: 244288-51-5
2-amino-4-chloro-6-di(4-methoxybenzyl)-amino-5-pyrimidine carbaldehyde

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; for 1.25h;

Reference yield: 62.4%

: 6921-34-2
benzylmagnesium chloride

: 244288-51-5
2-amino-4-chloro-6-di(4-methoxybenzyl)-amino-5-pyrimidine carbaldehyde

: 244288-55-9
2-amino-4-chloro-6-di-(4-methoxybenzyl)amino-5-(1-hydroxy-phenethyl)-pyrimidine

Guidance literature:: benzylmagnesium chloride; 2-amino-4-chloro-6-di(4-methoxybenzyl)-amino-5-pyrimidine carbaldehyde; In tetrahydrofuran; at 0 ℃; for 0.5h;

With water; ammonium chloride; In tetrahydrofuran; ethyl acetate;

Reference yield: 30.6%

: 100-49-2
cyclohexylmethyl alcohol

: 244288-51-5
2-amino-4-chloro-6-di(4-methoxybenzyl)-amino-5-pyrimidine carbaldehyde

: 244288-48-0
2-amino-4-cyclohexylmethoxy-6-di(4-methoxybenzyl)amino-5-pyrimidine carbaldehyde

Guidance literature:: cyclohexylmethyl alcohol; With sodium hydride; dimethyl sulfoxide; for 0.5h;

2-amino-4-chloro-6-di(4-methoxybenzyl)-amino-5-pyrimidine carbaldehyde; at 100 ℃; for 2h;