4-(2-furyl)-2,6-dimethyl-3,5-bis-N-(4-methylphenyl)-carbamoyl-1,4-dihydropyridine

Base Information

Chemical Name:4-(2-furyl)-2,6-dimethyl-3,5-bis-N-(4-methylphenyl)-carbamoyl-1,4-dihydropyridine
CAS No.:1296785-23-3
Molecular Formula:C₂₇H₂₇N₃O₃
Molecular Weight:441.53
Hs Code.:

Synonyms:4-(2-furyl)-2,6-dimethyl-3,5-bis-N-(4-methylphenyl)-carbamoyl-1,4-dihydropyridine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-(2-furyl)-2,6-dimethyl-3,5-bis-N-(4-methylphenyl)-carbamoyl-1,4-dihydropyridine

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Technology Process of 4-(2-furyl)-2,6-dimethyl-3,5-bis-N-(4-methylphenyl)-carbamoyl-1,4-dihydropyridine

There total 2 articles about 4-(2-furyl)-2,6-dimethyl-3,5-bis-N-(4-methylphenyl)-carbamoyl-1,4-dihydropyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 98-01-1
furfural

: 2415-85-2
3-oxo-N-(p-tolyl)butanamide

: 1296785-23-3
4-(2-furyl)-2,6-dimethyl-3,5-bis-N-(4-methylphenyl)-carbamoyl-1,4-dihydropyridine

Guidance literature:: With ammonium acetate; silica gel; for 0.075h; Microwave irradiation;
DOI:10.1016/j.ejmech.2011.02.003

Reference yield:

: 106-49-0,12221-03-3
p-toluidine

: 1296785-23-3
4-(2-furyl)-2,6-dimethyl-3,5-bis-N-(4-methylphenyl)-carbamoyl-1,4-dihydropyridine

Guidance literature:: Multi-step reaction with 2 steps

1: potassium tert-butylate / 0.08 h / Microwave irradiation

2: ammonium acetate; silica gel / 0.07 h / Microwave irradiation

With potassium tert-butylate; ammonium acetate; silica gel; 2: Hantzsch condensation;
DOI:10.1016/j.ejmech.2011.02.003