(1S,2S)-(-)-1,2-DIAMINOCYCLOHEXANE-N,N'-BIS(2'-DIPHENYLPHOSPHINOBENZOYL)

Base Information

• Chemical Name: (1S,2S)-(-)-1,2-DIAMINOCYCLOHEXANE-N,N'-BIS(2'-DIPHENYLPHOSPHINOBENZOYL)
• CAS No.: 169689-05-8
• Molecular Formula: C₄₄H₄₀N₂O₂P₂
• Molecular Weight: 690.761
• Mol file: 169689-05-8.mol

Synonyms:Benzamide,N,N'-1,2-cyclohexanediylbis[2-(diphenylphosphino)-, (1S-trans)-;(S,S)-Trostligand;

Chemical Property of (1S,2S)-(-)-1,2-DIAMINOCYCLOHEXANE-N,N'-BIS(2'-DIPHENYLPHOSPHINOBENZOYL)

Chemical Property:

• Melting Point: 134-136 °C
• Boiling Point: 817.0±65.0 °C(Predicted)
• PKA: 13.35±0.40(Predicted)
• PSA: 85.38000
• LogP: 7.45580
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

99%, ^*data from raw suppliers

(1S,2S)-(-)-1,2-Diaminocyclohexane-N,N'-bis(2'-diphenylphosphinobenzoyl), 95% (S,S)-DACH-Phenyl Trost Ligand ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: Trost Ligands for Asymmetric Allylic Alkylation

Technology Process of (1S,2S)-(-)-1,2-DIAMINOCYCLOHEXANE-N,N'-BIS(2'-DIPHENYLPHOSPHINOBENZOYL)

There total 5 articles about (1S,2S)-(-)-1,2-DIAMINOCYCLOHEXANE-N,N'-BIS(2'-DIPHENYLPHOSPHINOBENZOYL) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.9%

ortho-diphenylphosphinobenzoic acid (17261-28-8) + (1R,2R)-1,2-diaminocyclohexane (20439-47-8) → (1R,2R)-1,2-bis[(2-diphenylphosphanyl)benzoylamino]cyclohexane (138517-61-0,169689-05-8)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; for 6h; Ambient temperature;

DOI:10.1021/ja00050a013

Reference yield:

(±)-trans-1,2-diaminocyclohexane + ortho-diphenylphosphinobenzoic acid (17261-28-8) → (+)-1,2-diaminocyclohexyl-N,N'-bis(2'-diphenylphosphobenzoyl) (169689-05-8)

Guidance literature:

With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 16h; Inert atmosphere;

Reference yield:

(±)-trans-1,2-diaminocyclohexane + ortho-diphenylphosphinobenzoic acid (17261-28-8) → chiral 1,2-diaminocyclohexane based Trost ligand (169689-05-8)

Guidance literature:

With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 6h; Inert atmosphere;

upstream raw materials:

ortho-diphenylphosphinobenzoic acid

(1R,2R)-1,2-diaminocyclohexane

(1R,2R)-cyclohex-4-ene-1,2-diamine

trans-1,2-Diaminocyclohexane

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 169689-05-8 (1S,2S)-(-)-1,2-DIAMINOCYCLOHEXANE-N,N'-BIS(2'-DIPHENYLPHOSPHINOBENZOYL)

Send

Send

Metric Ton KG G Pound L ML

Send

Send