(S)-1-(1-{[2-chloro-4-(4-fluorophenyl)quinolin-7-yl]methyl}-1H-1,2,3-triazol-4-yl)-1-(trifluoromethyl)propyl 4-nitrobenzoate

Base Information

Chemical Name:(S)-1-(1-{[2-chloro-4-(4-fluorophenyl)quinolin-7-yl]methyl}-1H-1,2,3-triazol-4-yl)-1-(trifluoromethyl)propyl 4-nitrobenzoate
CAS No.:1044278-93-4
Molecular Formula:C₂₉H₂₀ClF₄N₅O₄
Molecular Weight:613.956
Hs Code.:

Synonyms:(S)-1-(1-{[2-chloro-4-(4-fluorophenyl)quinolin-7-yl]methyl}-1H-1,2,3-triazol-4-yl)-1-(trifluoromethyl)propyl 4-nitrobenzoate

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Chemical Property of (S)-1-(1-{[2-chloro-4-(4-fluorophenyl)quinolin-7-yl]methyl}-1H-1,2,3-triazol-4-yl)-1-(trifluoromethyl)propyl 4-nitrobenzoate

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Technology Process of (S)-1-(1-{[2-chloro-4-(4-fluorophenyl)quinolin-7-yl]methyl}-1H-1,2,3-triazol-4-yl)-1-(trifluoromethyl)propyl 4-nitrobenzoate

There total 1 articles about (S)-1-(1-{[2-chloro-4-(4-fluorophenyl)quinolin-7-yl]methyl}-1H-1,2,3-triazol-4-yl)-1-(trifluoromethyl)propyl 4-nitrobenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1044278-92-3
7-(azidomethyl)-2-chloro-4-(4-fluorophenyl)quinoline

: 1044277-04-4
(S)-1-ethyl-1-(trifluoromethyl)prop-2-yn-1-yl 4-nitrobenzoate

: 1044278-93-4
(S)-1-(1-{[2-chloro-4-(4-fluorophenyl)quinolin-7-yl]methyl}-1H-1,2,3-triazol-4-yl)-1-(trifluoromethyl)propyl 4-nitrobenzoate

Guidance literature:: 7-(azidomethyl)-2-chloro-4-(4-fluorophenyl)quinoline; (S)-1-ethyl-1-(trifluoromethyl)prop-2-yn-1-yl 4-nitrobenzoate; With copper(l) iodide; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at 20 ℃; for 16h;

With water; ammonium chloride; In tetrahydrofuran;

Reference yield:

: 1044278-93-4
(S)-1-(1-{[2-chloro-4-(4-fluorophenyl)quinolin-7-yl]methyl}-1H-1,2,3-triazol-4-yl)-1-(trifluoromethyl)propyl 4-nitrobenzoate

: 1044278-89-8
(S)-2-(1-{[2-chloro-4-(4-fluorophenyl)quinolin-7-yl]methyl}-1H-1,2,3-triazol-4-yl)-1,1,1-trifluorobutan-2-ol

Guidance literature:: (S)-1-(1-{[2-chloro-4-(4-fluorophenyl)quinolin-7-yl]methyl}-1H-1,2,3-triazol-4-yl)-1-(trifluoromethyl)propyl 4-nitrobenzoate; With lithium hydroxide; water; In tetrahydrofuran; at 20 ℃; for 5h;

With water; ammonium chloride; In tetrahydrofuran;