N,N,6-trimethyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-ylchloroacetamide hydrochloride

Base Information

• Chemical Name: N,N,6-trimethyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-ylchloroacetamide hydrochloride
• CAS No.: 118026-15-6
• Molecular Formula: C₁₉H₂₀ClN₃O*ClH
• Molecular Weight: 378.301
• Mol file: 118026-15-6.mol

Synonyms:N,N,6-trimethyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-ylchloroacetamide hydrochloride

Chemical Property of N,N,6-trimethyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-ylchloroacetamide hydrochloride

Chemical Property:

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N,N,6-trimethyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-ylchloroacetamide hydrochloride

There total 2 articles about N,N,6-trimethyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-ylchloroacetamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N,N,6-trimethyl-2-(4-methylphenyl)-imidazo[1,2-α]pyridine-3-α-hydroxyacetamide (118026-14-5) → N,N,6-trimethyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-ylchloroacetamide hydrochloride (118026-15-6)

Guidance literature:

With thionyl chloride; In 1,2-dichloro-ethane; at 30 - 35 ℃; for 16h;

Reference yield:

→ N,N,6-trimethyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-ylchloroacetamide hydrochloride (118026-15-6) + N,N,6-trimethyl-2-(4-methylphenyl)-imidazo[1,2-α]pyridine-3-α-hydroxyacetamide (118026-14-5)

Guidance literature:

Reference yield: 74.8%

N,N,6-trimethyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-ylchloroacetamide hydrochloride (118026-15-6) → N,N,6-trimethyl-2-(4-methylphenyl)-imidazo[1,2-a]pyridine-3-acetamide hydrochloride

Guidance literature:

With palladium on activated charcoal; In methanol; at 35 - 45 ℃; under 150.015 - 675.068 Torr; Concentration; Pressure; Inert atmosphere; Large scale;

upstream raw materials:

N,N,6-trimethyl-2-(4-methylphenyl)-imidazo[1,2-α]pyridine-3-α-hydroxyacetamide