Technology Process of tris<2,6-bis(difluoromethyl)phenyl>arsine oxide
There total 4 articles about tris<2,6-bis(difluoromethyl)phenyl>arsine oxide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
dihydrogen peroxide;
In
acetone;
at 75 ℃;
for 16h;
DOI:10.1021/ja00366a006
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1.) CrOr, Acetic ahhydride, conc. H2SO4, 2.) aq. HCl / 1.) 0 deg C (3 h), 15 deg C (2 h), 2.) dioxane, 4 h
2: 60 percent / SF4 / CH2Cl2 / 9 h / 83 - 85 °C
3: 1.) n-butyllithium, 2.) AsCl3 / 1.) - 30 deg C, 2 h, 2.) 25 deg C (20 h) , reflux (8 h)
4: 80 percent / aq. H2O2 / acetone / 16 h / 75 °C
With
hydrogenchloride; n-butyllithium; sulfuric acid; sulfur tetrafluoride; dihydrogen peroxide; acetic anhydride; arsenic trichloride;
In
dichloromethane; acetone;
DOI:10.1021/ja00366a006
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 60 percent / SF4 / CH2Cl2 / 9 h / 83 - 85 °C
2: 1.) n-butyllithium, 2.) AsCl3 / 1.) - 30 deg C, 2 h, 2.) 25 deg C (20 h) , reflux (8 h)
3: 80 percent / aq. H2O2 / acetone / 16 h / 75 °C
With
n-butyllithium; sulfur tetrafluoride; dihydrogen peroxide; arsenic trichloride;
In
dichloromethane; acetone;
DOI:10.1021/ja00366a006
