1-aminocyclopentanecarboxylic acid [1-(3-morpholin-4-ylpropylcarbamoyl)-2-phenylethyl]amide

Base Information

• Chemical Name: 1-aminocyclopentanecarboxylic acid [1-(3-morpholin-4-ylpropylcarbamoyl)-2-phenylethyl]amide
• CAS No.: 734530-08-6
• Molecular Formula: C₂₂H₃₄N₄O₃
• Molecular Weight: 402.537

Synonyms:1-aminocyclopentanecarboxylic acid [1-(3-morpholin-4-ylpropylcarbamoyl)-2-phenylethyl]amide

Chemical Property of 1-aminocyclopentanecarboxylic acid [1-(3-morpholin-4-ylpropylcarbamoyl)-2-phenylethyl]amide

Chemical Property:

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Technology Process of 1-aminocyclopentanecarboxylic acid [1-(3-morpholin-4-ylpropylcarbamoyl)-2-phenylethyl]amide

There total 1 articles about 1-aminocyclopentanecarboxylic acid [1-(3-morpholin-4-ylpropylcarbamoyl)-2-phenylethyl]amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C16H25N3O2*2HCl + 1-amino-1-cyclopentanecarboxylic acid (52-52-8) → 1-aminocyclopentanecarboxylic acid [1-(3-morpholin-4-ylpropylcarbamoyl)-2-phenylethyl]amide (734530-08-6)

Guidance literature:

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In dichloromethane; N,N-dimethyl-formamide; at 20 ℃; for 48h;

DOI:10.1021/jm070289w

Reference yield: 40.0%

1-aminocyclopentanecarboxylic acid [1-(3-morpholin-4-ylpropylcarbamoyl)-2-phenylethyl]amide (734530-08-6) + 4-bromophenyl isocyanate (2493-02-9) → C29H38BrN5O4

Guidance literature:

at 20 - 40 ℃;

DOI:10.1021/jm070289w

Reference yield:

1-aminocyclopentanecarboxylic acid [1-(3-morpholin-4-ylpropylcarbamoyl)-2-phenylethyl]amide (734530-08-6) + 6-Chlorbenzothiophen-2-carbonylchlorid (105191-51-3) → C31H37ClN4O4S

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 5h;

DOI:10.1021/jm070289w

upstream raw materials:

1-amino-1-cyclopentanecarboxylic acid

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