Carbamic acid, (3-hydroxybutyl)-, 1,1-dimethylethyl ester (9CI)

Base Information

• Chemical Name: Carbamic acid, (3-hydroxybutyl)-, 1,1-dimethylethyl ester (9CI)
• CAS No.: 167216-30-0
• Molecular Formula: C9H19 N O3
• Molecular Weight: 189.255
• Hs Code.: 2924199090
• Mol file: 167216-30-0.mol

Synonyms:Carbamic acid, (3-hydroxybutyl)-, 1,1-dimethylethyl ester (9CI)

Chemical Property of Carbamic acid, (3-hydroxybutyl)-, 1,1-dimethylethyl ester (9CI)

Chemical Property:

• Boiling Point: 301.4±25.0 °C(Predicted)
• PKA: 12.75±0.46(Predicted)
• PSA: 62.05000
• Density: 1.010±0.06 g/cm3(Predicted)
• LogP: 1.48640
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

tert-Butyl(3-hydroxybutyl)carbamate 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Carbamic acid, (3-hydroxybutyl)-, 1,1-dimethylethyl ester (9CI)

There total 5 articles about Carbamic acid, (3-hydroxybutyl)-, 1,1-dimethylethyl ester (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(3-Oxo-butyl)-carbamic acid tert-butyl ester (54614-95-8) → 4-(N-(tert-butyloxycarbonyl)amino)-2-butanol (167216-30-0)

Guidance literature:

With sodium tetrahydroborate; In methanol; at 0 - 20 ℃;

DOI:10.1021/ol900806m

Reference yield: 99.0%

di-tert-butyl dicarbonate (24424-99-5) + 4-amino-butan-2-ol (114963-62-1,127912-49-6,39884-48-5) → 4-(N-(tert-butyloxycarbonyl)amino)-2-butanol (167216-30-0)

Guidance literature:

In dichloromethane; for 18h;

Reference yield: 91.0%

tert-butyl 3-benzyloxy-butylcarbamate → 4-(N-(tert-butyloxycarbonyl)amino)-2-butanol (167216-30-0)

Guidance literature:

With 20% palladium hydroxide-activated charcoal; hydrogen; In methanol; at 20 ℃; under 750.075 Torr; Schlenk technique;

DOI:10.1002/cctc.201800509

upstream raw materials:

di-tert-butyl dicarbonate

4-amino-butan-2-ol

(3-Oxo-butyl)-carbamic acid tert-butyl ester

tert-butyl carbazate

Downstream raw materials:

(3-Oxo-butyl)-carbamic acid tert-butyl ester