methyl 2-(4-bromophenyl)-2-(piperidin-1-yl)acetatetate

Base Information

• Chemical Name: methyl 2-(4-bromophenyl)-2-(piperidin-1-yl)acetatetate
• CAS No.: 1394823-80-3
• Molecular Formula: C₁₄H₁₈BrNO₂
• Molecular Weight: 312.206
• Mol file: 1394823-80-3.mol

Synonyms:methyl 2-(4-bromophenyl)-2-(piperidin-1-yl)acetatetate

Chemical Property of methyl 2-(4-bromophenyl)-2-(piperidin-1-yl)acetatetate

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of methyl 2-(4-bromophenyl)-2-(piperidin-1-yl)acetatetate

There total 2 articles about methyl 2-(4-bromophenyl)-2-(piperidin-1-yl)acetatetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

piperidine (110-89-4) + (4-bromo-phenyl)-acetic acid methyl ester (41841-16-1) → methyl 2-(4-bromophenyl)-2-(piperidin-1-yl)acetatetate (1394823-80-3)

Guidance literature:

With lithium perchlorate; potassium iodide; In acetonitrile; at 20 ℃; Electrolysis; Inert atmosphere;

DOI:10.1021/acs.joc.1c00944

Reference yield: 64.0%

piperidine (110-89-4) + methyl 2-(4-bromophenyl)-2-diazoacetate (264881-99-4) → methyl 2-(4-bromophenyl)-2-(piperidin-1-yl)acetatetate (1394823-80-3)

Guidance literature:

at 102 ℃; for 12h; Inert atmosphere;

DOI:10.1021/ol3020754

upstream raw materials:

piperidine

methyl 2-(4-bromophenyl)-2-diazoacetate

(4-bromo-phenyl)-acetic acid methyl ester