2,2,4,4-tetrachloro-7-(4-fluorobenzyl)-1,3,5,7,11-pentaaza-2λ5,4λ5,6λ5-triphosphaspiro[5.5]undeca-1,3,5-triene

Base Information

• Chemical Name: 2,2,4,4-tetrachloro-7-(4-fluorobenzyl)-1,3,5,7,11-pentaaza-2λ5,4λ5,6λ5-triphosphaspiro[5.5]undeca-1,3,5-triene
• CAS No.: 161799-50-4
• Molecular Formula: C₁₀H₁₃Cl₄FN₅P₃
• Molecular Weight: 456.978
• Mol file: 161799-50-4.mol

Synonyms:2,2,4,4-tetrachloro-7-(4-fluorobenzyl)-1,3,5,7,11-pentaaza-2λ5,4λ5,6λ5-triphosphaspiro[5.5]undeca-1,3,5-triene

Chemical Property of 2,2,4,4-tetrachloro-7-(4-fluorobenzyl)-1,3,5,7,11-pentaaza-2λ5,4λ5,6λ5-triphosphaspiro[5.5]undeca-1,3,5-triene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,2,4,4-tetrachloro-7-(4-fluorobenzyl)-1,3,5,7,11-pentaaza-2λ5,4λ5,6λ5-triphosphaspiro[5.5]undeca-1,3,5-triene

There total 3 articles about 2,2,4,4-tetrachloro-7-(4-fluorobenzyl)-1,3,5,7,11-pentaaza-2λ5,4λ5,6λ5-triphosphaspiro[5.5]undeca-1,3,5-triene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

C10H15FN2 (97146-01-5) → 2,2,4,4-tetrachloro-7-(4-fluorobenzyl)-1,3,5,7,11-pentaaza-2λ5,4λ5,6λ5-triphosphaspiro[5.5]undeca-1,3,5-triene (161799-50-4)

Guidance literature:

With 2,2,4,4,6,6-hexachloro-1,3,5-triaza-2,4,6-triphosphorine; triethylamine; In tetrahydrofuran; at 20 ℃; for 26h; Inert atmosphere;

DOI:10.1016/j.poly.2011.08.035

Reference yield:

C10H13FN2 (203582-63-2) → 2,2,4,4-tetrachloro-7-(4-fluorobenzyl)-1,3,5,7,11-pentaaza-2λ5,4λ5,6λ5-triphosphaspiro[5.5]undeca-1,3,5-triene (161799-50-4)

Guidance literature:

Multi-step reaction with 2 steps

1: reducting agent

2: 2,2,4,4,6,6-hexachloro-1,3,5-triaza-2,4,6-triphosphorine; triethylamine / tetrahydrofuran / 26 h / 20 °C / Inert atmosphere

With 2,2,4,4,6,6-hexachloro-1,3,5-triaza-2,4,6-triphosphorine; triethylamine; In tetrahydrofuran;

DOI:10.1016/j.poly.2011.08.035

Reference yield:

4-fluorobenzaldehyde (459-57-4) → 2,2,4,4-tetrachloro-7-(4-fluorobenzyl)-1,3,5,7,11-pentaaza-2λ5,4λ5,6λ5-triphosphaspiro[5.5]undeca-1,3,5-triene (161799-50-4)

Guidance literature:

Multi-step reaction with 3 steps

1: methanol

2: reducting agent

3: 2,2,4,4,6,6-hexachloro-1,3,5-triaza-2,4,6-triphosphorine; triethylamine / tetrahydrofuran / 26 h / 20 °C / Inert atmosphere

With 2,2,4,4,6,6-hexachloro-1,3,5-triaza-2,4,6-triphosphorine; triethylamine; In tetrahydrofuran; methanol;

DOI:10.1016/j.poly.2011.08.035

upstream raw materials:

C₁₀H₁₃FN₂

C₁₀H₁₅FN₂

4-fluorobenzaldehyde