2,5-dimethylfuran-3-sulfonyl Chloride

Base Information

• Chemical Name: 2,5-dimethylfuran-3-sulfonyl Chloride
• CAS No.: 166964-26-7
• Molecular Formula: C6H7ClO3S
• Molecular Weight: 194.639
• Hs Code.: 2932190090
• European Community (EC) Number: 848-347-4
• DSSTox Substance ID: DTXSID60383523
• Mol file: 166964-26-7.mol

Synonyms:2,5-dimethylfuran-3-sulfonyl Chloride;166964-26-7;2,5-Dimethyl-3-furansulfonyl chloride;C6H7ClO3S;3-Furansulfonylchloride, 2,5-dimethyl-;SCHEMBL392050;DTXSID60383523;PIXAQZAVANAGLE-UHFFFAOYSA-N;MFCD04115370;2,5-dimethylfuran-3-sulfonylChloride;2,5-dimethyl-furan-3-sulfonylchloride;2,5-dimethylfuran 3-sulfonyl chloride;AKOS006230638;SB61577;2,5-Dimethylfuran-3-sulphonyl chloride;3-Furansulfonyl chloride, 2,5-dimethyl-;CS-0447925;EN300-78579;2,5-dimethyl-3-furansulfonyl chloride, AldrichCPR;J-507363

Chemical Property of 2,5-dimethylfuran-3-sulfonyl Chloride

Chemical Property:

• Vapor Pressure: 0.0171mmHg at 25°C
• Refractive Index: 1.507
• Boiling Point: 263.1 °C at 760 mmHg
• Flash Point: 112.9 °C
• PSA: 55.66000
• Density: 1.376 g/cm³
• LogP: 2.90470
• Storage Temp.: 2-8°C
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 193.9804429
• Heavy Atom Count: 11
• Complexity: 231

Purity/Quality:

98%min ^*data from raw suppliers

2,5-Dimethyl-3-furansulfonylChloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C,Xi
• Statements: 36
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=C(O1)C)S(=O)(=O)Cl

Technology Process of 2,5-dimethylfuran-3-sulfonyl Chloride

There total 3 articles about 2,5-dimethylfuran-3-sulfonyl Chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

→ 2,5-dimethyl-furan-3-ylsulphonyl chloride (166964-26-7)

Guidance literature:

Reference yield: 22.0%

2,5-dimethylfuran (625-86-5) → 2,5-dimethyl-furan-3-ylsulphonyl chloride (166964-26-7)

Guidance literature:

With sulfuryl dichloride; In N,N-dimethyl-formamide;

Reference yield:

2,5-dimethylfuran (625-86-5) + sulfuryl dichloride (7791-25-5) → 2,5-dimethyl-furan-3-ylsulphonyl chloride (166964-26-7)

Guidance literature:

In N,N-dimethyl-formamide;

upstream raw materials:

2,5-dimethylfuran

sulfuryl dichloride

Downstream raw materials:

N-(2,4-difluoro-3-(3-(9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-yl)pyridin-2-ylamino)phenyl)-2,5-dimethylfuran-3-sulfonamide

Refernces

• 1、 -. "Biphenylsulfonamides and derivatives thereof that modulate the activity of endothelin". . . Retrieved 2008/06/13.
• 2、 -. "THIENYL-, FURYL- AND PYRROLYL- SULFONAMIDES AND DERIVATIVES THEREOF THAT MODULATE THE ACTIVITY OF ENDOTHELIN". . . Retrieved 2008/06/13.