ethyl (2E,4E,6Z)-8-tert-butyldiphenylsiloxy-2,6-dimethylocta-2,4,6-trienoate

Base Information

• Chemical Name: ethyl (2E,4E,6Z)-8-tert-butyldiphenylsiloxy-2,6-dimethylocta-2,4,6-trienoate
• CAS No.: 181053-79-2
• Molecular Formula: C₂₈H₃₆O₃Si
• Molecular Weight: 448.678
• Mol file: 181053-79-2.mol

Synonyms:ethyl (2E,4E,6Z)-8-tert-butyldiphenylsiloxy-2,6-dimethylocta-2,4,6-trienoate

Chemical Property of ethyl (2E,4E,6Z)-8-tert-butyldiphenylsiloxy-2,6-dimethylocta-2,4,6-trienoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl (2E,4E,6Z)-8-tert-butyldiphenylsiloxy-2,6-dimethylocta-2,4,6-trienoate

There total 5 articles about ethyl (2E,4E,6Z)-8-tert-butyldiphenylsiloxy-2,6-dimethylocta-2,4,6-trienoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

tert-butylchlorodiphenylsilane (58479-61-1) + ethyl (2E,4E,6Z)-8-hydroxy-2,6-dimethylocta-2,4,6-trienoate (181053-78-1) → ethyl (2E,4E,6Z)-8-tert-butyldiphenylsiloxy-2,6-dimethylocta-2,4,6-trienoate (181053-79-2)

Guidance literature:

DOI:10.1246/cl.1996.671

Reference yield:

[(2E)-3-ethoxycarbonylbut-2-enyl][1-isopropenyl-2-(tert-butyldimethylsiloxy)ethyl]dimethylammonium bromide → ethyl (2E,4E,6Z)-8-tert-butyldiphenylsiloxy-2,6-dimethylocta-2,4,6-trienoate (181053-79-2)

Guidance literature:

Multi-step reaction with 4 steps

1: KOEt / ethanol / 5 h / -70 °C

2: peracetic acid, Na₂CO₃ / CH₂Cl₂ / -60 °C

3: 100 percent / n-Bu₄NF

4: 98 percent

With peracetic acid; potassium ethoxide; tetrabutyl ammonium fluoride; sodium carbonate; In ethanol; dichloromethane;

DOI:10.1246/cl.1996.671

Reference yield:

(2E,6Z)-8-(tert-Butyl-dimethyl-silanyloxy)-4-dimethylamino-2,6-dimethyl-octa-2,6-dienoic acid ethyl ester (181053-71-4) → ethyl (2E,4E,6Z)-8-tert-butyldiphenylsiloxy-2,6-dimethylocta-2,4,6-trienoate (181053-79-2)

Guidance literature:

Multi-step reaction with 3 steps

1: peracetic acid, Na₂CO₃ / CH₂Cl₂ / -60 °C

2: 100 percent / n-Bu₄NF

3: 98 percent

With peracetic acid; tetrabutyl ammonium fluoride; sodium carbonate; In dichloromethane;

DOI:10.1246/cl.1996.671

upstream raw materials:

tert-butylchlorodiphenylsilane

ethyl (2E,4E,6Z)-8-hydroxy-2,6-dimethylocta-2,4,6-trienoate

ethyl (2E,4E,6Z)-8-tert-butyldimethylsiloxy-2,6-dimethylocta-2,4,6-trienoate

(3E,6Z)-8-(tert-Butyl-dimethyl-silanyloxy)-2-(N,N-dimethyl-aminooxy)-2,6-dimethyl-octa-3,6-dienoic acid ethyl ester

Downstream raw materials:

(2E,4E,6Z)-8-tert-butyldiphenylsiloxy-2,6-dimethylocta-2,4,6-trien-1-ol

2-cis-Vitamin-A

(2E,4E,6Z)-8-tert-butyldiphenylsiloxy-2,6-dimethylocta-2,4,6-trienal

9-(2',6',6'-trimethylcyclohex-1'-enyl)-8-acetoxy-3,7-dimethyl-9-(p-tolylsulfonyl)nona-2Z,4E,6E-trien-1-ol