1-Cyclohexene-1-carboxaldehyde,3-hydroxy-4-(1-methylethyl)-,(3S,4R)-(9CI)

Base Information

• Chemical Name: 1-Cyclohexene-1-carboxaldehyde,3-hydroxy-4-(1-methylethyl)-,(3S,4R)-(9CI)
• CAS No.: 166583-62-6
• Molecular Formula: C₁₀H₁₆O₂
• Molecular Weight: 168.236
• Mol file: 166583-62-6.mol

Synonyms:1-Cyclohexene-1-carboxaldehyde,3-hydroxy-4-(1-methylethyl)-, (3S-cis)-

Chemical Property of 1-Cyclohexene-1-carboxaldehyde,3-hydroxy-4-(1-methylethyl)-,(3S,4R)-(9CI)

Chemical Property:

• Boiling Point: 281.6±40.0 °C(Predicted)
• PKA: 14.34±0.60(Predicted)
• PSA: 37.30000
• Density: 1.096±0.06 g/cm3(Predicted)
• LogP: 1.53860

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-Cyclohexene-1-carboxaldehyde,3-hydroxy-4-(1-methylethyl)-,(3S,4R)-(9CI)

There total 12 articles about 1-Cyclohexene-1-carboxaldehyde,3-hydroxy-4-(1-methylethyl)-,(3S,4R)-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 22.0%

2α-isopropyl-8-oxabicyclo[3.2.1]oct-6-ene (147729-85-9) → 3-hydroxyphellandral (145544-91-8,166583-62-6,152246-70-3)

Guidance literature:

With isocyanate de chlorosulfonyle; In dichloromethane; for 192h; Ambient temperature; unexpected rearrangement;

Reference yield: 5.1%

(+/-)-1-(1,3-dithian-2-yl)-4-isopropyl-2-cyclohexen-1-ol → 3-hydroxyphellandral (145544-91-8,166583-62-6,152246-70-3) + (+/-)-epi-eucamalol (145544-91-8,166583-62-6,152246-70-3)

Guidance literature:

With boron trifluoride diethyl etherate; mercury(II) oxide; In tetrahydrofuran; water; for 3h; Heating;

DOI:10.1021/jf00035a065

Reference yield: 5.1%

(+/-)-1-(1,3-dithian-2-yl)-4-isopropyl-2-cyclohexen-1-ol → 3-hydroxyphellandral (145544-91-8,166583-62-6,152246-70-3) + (+/-)-epi-eucamalol (145544-91-8,166583-62-6,152246-70-3)

Guidance literature:

With boron trifluoride diethyl etherate; mercury(II) oxide; In tetrahydrofuran; water; for 3h; Heating;

DOI:10.1021/jf00035a065

upstream raw materials:

2α-isopropyl-8-oxabicyclo[3.2.1]oct-6-ene

cryptone

(S)-(-)-perillaldehyde

(S)-4-Isopropyl-cyclohex-1-enecarbaldehyde