(2S,3S)-2-(4-methylphenylsulfonamido)-3-[(2S)-1-(tert-butyloxycarbonyl)tetrahydro-1H-2-pyrrolyl]carboxamido-3-phenylpropanoic acid methyl ester

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Chemical Name:(2S,3S)-2-(4-methylphenylsulfonamido)-3-[(2S)-1-(tert-butyloxycarbonyl)tetrahydro-1H-2-pyrrolyl]carboxamido-3-phenylpropanoic acid methyl ester
CAS No.:1200953-66-7
Molecular Formula:C₂₇H₃₅N₃O₇S
Molecular Weight:545.657
Hs Code.:

(2S,3S)-2-(4-methylphenylsulfonamido)-3-[(2S)-1-(tert-butyloxycarbonyl)tetrahydro-1H-2-pyrrolyl]carboxamido-3-phenylpropanoic acid methyl ester

Synonyms:(2S,3S)-2-(4-methylphenylsulfonamido)-3-[(2S)-1-(tert-butyloxycarbonyl)tetrahydro-1H-2-pyrrolyl]carboxamido-3-phenylpropanoic acid methyl ester

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Chemical Property of (2S,3S)-2-(4-methylphenylsulfonamido)-3-[(2S)-1-(tert-butyloxycarbonyl)tetrahydro-1H-2-pyrrolyl]carboxamido-3-phenylpropanoic acid methyl ester

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Technology Process of (2S,3S)-2-(4-methylphenylsulfonamido)-3-[(2S)-1-(tert-butyloxycarbonyl)tetrahydro-1H-2-pyrrolyl]carboxamido-3-phenylpropanoic acid methyl ester

There total 1 articles about (2S,3S)-2-(4-methylphenylsulfonamido)-3-[(2S)-1-(tert-butyloxycarbonyl)tetrahydro-1H-2-pyrrolyl]carboxamido-3-phenylpropanoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 15761-39-4,59433-50-0
1-(tert-butoxycarbonyl)-L-proline

: 1200953-64-5
(2S,3S)-3-amino-2-[(4-methylphenyl)sulfonamido]-3-phenylpropanoic acid methyl ester

: 1200953-66-7
(2S,3S)-2-(4-methylphenylsulfonamido)-3-[(2S)-1-(tert-butyloxycarbonyl)tetrahydro-1H-2-pyrrolyl]carboxamido-3-phenylpropanoic acid methyl ester

Guidance literature:: 1-(tert-butoxycarbonyl)-L-proline; With benzotriazol-1-ol; In dichloromethane; at 0 ℃;

(2S,3S)-3-amino-2-[(4-methylphenyl)sulfonamido]-3-phenylpropanoic acid methyl ester; With dicyclohexyl-carbodiimide; In dichloromethane; at 0 ℃;
DOI:10.1021/jo902106r

Reference yield: 80.0%

: 1200953-66-7
(2S,3S)-2-(4-methylphenylsulfonamido)-3-[(2S)-1-(tert-butyloxycarbonyl)tetrahydro-1H-2-pyrrolyl]carboxamido-3-phenylpropanoic acid methyl ester

: 1200953-53-2
(2S,3S)-2-(4-methylphenylsulfonamido)-3-phenyl-3-((S)-pyrrolidine-2-carboxamido)propanoic acid methyl ester

Guidance literature:: (2S,3S)-2-(4-methylphenylsulfonamido)-3-[(2S)-1-(tert-butyloxycarbonyl)tetrahydro-1H-2-pyrrolyl]carboxamido-3-phenylpropanoic acid methyl ester; With formic acid; at 0 - 20 ℃;

With ammonia; water; at 0 ℃;
DOI:10.1021/jo902106r