5S-(1R-hydroxy-3-phenylpropyl)-3,4R-bis-(4-methoxyphenyl)oxazolidin-2-one

Base Information

Chemical Name:5S-(1R-hydroxy-3-phenylpropyl)-3,4R-bis-(4-methoxyphenyl)oxazolidin-2-one
CAS No.:1053172-99-8
Molecular Formula:C₂₆H₂₇NO₅
Molecular Weight:433.504
Hs Code.:

Synonyms:5S-(1R-hydroxy-3-phenylpropyl)-3,4R-bis-(4-methoxyphenyl)oxazolidin-2-one

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5S-(1R-hydroxy-3-phenylpropyl)-3,4R-bis-(4-methoxyphenyl)oxazolidin-2-one

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Technology Process of 5S-(1R-hydroxy-3-phenylpropyl)-3,4R-bis-(4-methoxyphenyl)oxazolidin-2-one

There total 8 articles about 5S-(1R-hydroxy-3-phenylpropyl)-3,4R-bis-(4-methoxyphenyl)oxazolidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 1053172-97-6
acetic acid 1R-[3,4R-bis-(4-methoxyphenyl)-2-oxo-oxazolidin-5S-yl]-3-phenylpropyl ester

: 1053172-99-8
5S-(1R-hydroxy-3-phenylpropyl)-3,4R-bis-(4-methoxyphenyl)oxazolidin-2-one

Guidance literature:: With methanol; potassium carbonate; at 25 ℃;

Reference yield:

: 1053172-96-5
3,4R-bis-(4-methoxyphenyl)-5S-(3-phenylpropionyl)oxazolidin-2-one

: 1053172-99-8
5S-(1R-hydroxy-3-phenylpropyl)-3,4R-bis-(4-methoxyphenyl)oxazolidin-2-one

: 1053173-00-4
5S-(1S-hydroxy-3-phenylpropyl)-3,4R-bis-(4-methoxyphenyl)oxazolidin-2-one

Guidance literature:: 3,4R-bis-(4-methoxyphenyl)-5S-(3-phenylpropionyl)oxazolidin-2-one; With sodium tetrahydroborate; In tetrahydrofuran; methanol; at 0 - 25 ℃;

With hydrogenchloride; In tetrahydrofuran; methanol; water;

Reference yield:

: 20296-07-5
1-hydroxy-4-phenyl-2-butanone

: 1053172-99-8
5S-(1R-hydroxy-3-phenylpropyl)-3,4R-bis-(4-methoxyphenyl)oxazolidin-2-one

: 1053173-00-4
5S-(1S-hydroxy-3-phenylpropyl)-3,4R-bis-(4-methoxyphenyl)oxazolidin-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: L-proline / dimethyl sulfoxide / 144 h / 25 °C

2: triethylamine / dichloromethane / -20 - 25 °C

3: sodium tetrahydroborate / tetrahydrofuran; methanol / 0 - 25 °C

With sodium tetrahydroborate; triethylamine; L-proline; In tetrahydrofuran; methanol; dichloromethane; dimethyl sulfoxide;