3-Methoxy Loratadine

Base Information

• Chemical Name: 3-Methoxy Loratadine
• CAS No.: 165739-73-1
• Molecular Formula: C₂₃H₂₅ClN₂O₃
• Molecular Weight: 412.916
• ChEMBL ID: CHEMBL3357024
• DSSTox Substance ID: DTXSID20593323
• Mol file: 165739-73-1.mol

Synonyms:3-Methoxy Loratadine;165739-73-1;CHEMBL3357024;ethyl 4-(13-chloro-6-methoxy-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidine-1-carboxylate;SCHEMBL7675089;DTXSID20593323;BDBM50031119;AKOS030255516;J-010225;Ethyl 4-(8-chloro-3-methoxy-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine-1-carboxylate

Chemical Property of 3-Methoxy Loratadine

Chemical Property:

• Vapor Pressure: 1.02E-12mmHg at 25°C
• Refractive Index: 1.603
• Boiling Point: 563.4°C at 760 mmHg
• Flash Point: 294.5°C
• PSA: 51.66000
• Density: 1.26g/cm³
• LogP: 4.83430
• XLogP3: 5.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 412.1553704
• Heavy Atom Count: 29
• Complexity: 615

Purity/Quality:

99% ^*data from raw suppliers

3-MethoxyLoratadine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)N1CCC(=C2C3=C(CCC4=C2N=CC(=C4)OC)C=C(C=C3)Cl)CC1
• Uses: 3-Methoxy Loratadine is useful as inhibitor of both farnesyl protein transferase and geranylgeranyl protein transferase in the treatment of cell-proliferative diseases.

Technology Process of 3-Methoxy Loratadine

There total 1 articles about 3-Methoxy Loratadine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 3-methoxyloratadine (165739-73-1)

Guidance literature:

Refernces

• 1、 -. "Tricyclic carbamate compounds useful for inhibition of G-protein function and for treatment of proliferative diseases". . . Retrieved 2008/06/13.