5'-(4,4'-dimethoxytrityl)-5-[1,2-diacetoxy-2-(3,4,5-trimethoxyphenyl)-ethyl]-2'-deoxyuridine

Base Information

Chemical Name:5'-(4,4'-dimethoxytrityl)-5-[1,2-diacetoxy-2-(3,4,5-trimethoxyphenyl)-ethyl]-2'-deoxyuridine
CAS No.:927683-63-4
Molecular Formula:C₄₅H₄₈N₂O₁₄
Molecular Weight:840.881
Hs Code.:

Synonyms:5'-(4,4'-dimethoxytrityl)-5-[1,2-diacetoxy-2-(3,4,5-trimethoxyphenyl)-ethyl]-2'-deoxyuridine

Suppliers and Price of 5'-(4,4'-dimethoxytrityl)-5-[1,2-diacetoxy-2-(3,4,5-trimethoxyphenyl)-ethyl]-2'-deoxyuridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 5'-(4,4'-dimethoxytrityl)-5-[1,2-diacetoxy-2-(3,4,5-trimethoxyphenyl)-ethyl]-2'-deoxyuridine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 5'-(4,4'-dimethoxytrityl)-5-[1,2-diacetoxy-2-(3,4,5-trimethoxyphenyl)-ethyl]-2'-deoxyuridine

There total 7 articles about 5'-(4,4'-dimethoxytrityl)-5-[1,2-diacetoxy-2-(3,4,5-trimethoxyphenyl)-ethyl]-2'-deoxyuridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 927683-62-3
5-[1,2-diacetoxy-2-(3,4,5-trimethoxyphenyl)-ethyl]-2'-deoxyuridine

: 40615-36-9
4,4'-dimethoxytrityl chloride

: 927683-63-4
5'-(4,4'-dimethoxytrityl)-5-[1,2-diacetoxy-2-(3,4,5-trimethoxyphenyl)-ethyl]-2'-deoxyuridine

Guidance literature:: In pyridine; at 0 - 25 ℃; for 16h;
DOI:10.1021/ja0678931

Reference yield:

: 5-(1-(3,4,5-trimethoxyphenyl)-vinyl)-2'-deoxyuridine

: 927683-63-4
5'-(4,4'-dimethoxytrityl)-5-[1,2-diacetoxy-2-(3,4,5-trimethoxyphenyl)-ethyl]-2'-deoxyuridine

Guidance literature:: Multi-step reaction with 5 steps

1: 86 percent / imidazole / dimethylformamide / 32 h / 25 °C

2: 83 percent / NMO; OsO₄ / acetone; H₂O / 1 h / 25 °C

3: 80 percent / pyridine / 16 h / 25 °C

4: 88 percent / TBAF / tetrahydrofuran / 16 h / 25 °C

5: 62 percent / pyridine / 16 h / 0 - 25 °C

With 1H-imidazole; osmium(VIII) oxide; N-methyl-2-indolinone; tetrabutyl ammonium fluoride; In tetrahydrofuran; pyridine; water; N,N-dimethyl-formamide; acetone;
DOI:10.1021/ja0678931

Reference yield:

: 3',5'-bis(t-butyl-dimethylsilyl)-5-(2-(3,4,5-trimethoxyphenyl)-vinyl)-2'-deoxyuridine

: 927683-63-4
5'-(4,4'-dimethoxytrityl)-5-[1,2-diacetoxy-2-(3,4,5-trimethoxyphenyl)-ethyl]-2'-deoxyuridine

Guidance literature:: Multi-step reaction with 4 steps

1: 83 percent / NMO; OsO₄ / acetone; H₂O / 1 h / 25 °C

2: 80 percent / pyridine / 16 h / 25 °C

3: 88 percent / TBAF / tetrahydrofuran / 16 h / 25 °C

4: 62 percent / pyridine / 16 h / 0 - 25 °C

With osmium(VIII) oxide; N-methyl-2-indolinone; tetrabutyl ammonium fluoride; In tetrahydrofuran; pyridine; water; acetone;
DOI:10.1021/ja0678931