C₅₅H₇₉N₅O₁₁

Base Information

• Chemical Name: C₅₅H₇₉N₅O₁₁
• CAS No.: 945496-86-6
• Molecular Formula: C₅₅H₇₉N₅O₁₁
• Molecular Weight: 986.259
• Mol file: 945496-86-6.mol

Synonyms:C₅₅H₇₉N₅O₁₁

Chemical Property of C₅₅H₇₉N₅O₁₁

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₅₅H₇₉N₅O₁₁

There total 19 articles about C₅₅H₇₉N₅O₁₁ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C21H24N2O5 (440679-63-0,945496-80-0) → C55H79N5O11 (945496-86-6)

Guidance literature:

Multi-step reaction with 8 steps

1: hydroxylamine hydrochloride / methanol / 0.33 h / 60 °C

2: SOCl₂ / 16 h / 0 - 20 °C

3: 2.89 g / NaHCO₃ / CH₂Cl₂ / 16 h / 20 °C

4: DIPEA / methanol

5: 100 percent / H₂ / Pd-C / methanol / 0.75 h / 20 °C

6: 0.425 g / EDC; HOAt; DMAP / dimethylformamide / 16 h / 20 °C

7: 100 percent / LiOH / tetrahydrofuran; H₂O / 12 h / 20 °C

8: 0.100 g / EDC / 24 h / 20 °C

With dmap; lithium hydroxide; thionyl chloride; 1-hydroxy-7-aza-benzotriazole; hydroxylamine hydrochloride; hydrogen; sodium hydrogencarbonate; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; N-ethyl-N,N-diisopropylamine; palladium on activated charcoal; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide;

DOI:10.1039/b703116e

Reference yield:

C21H24N2O5 → C55H79N5O11 (945496-86-6)

Guidance literature:

Multi-step reaction with 9 steps

1.1: TFA / CH₂Cl₂ / 1 h / 20 °C

1.2: 4.50 g / benzaldehyde / ethyl acetate / 0 - 20 °C

2.1: hydroxylamine hydrochloride / methanol / 0.33 h / 60 °C

3.1: SOCl₂ / 16 h / 0 - 20 °C

4.1: 2.89 g / NaHCO₃ / CH₂Cl₂ / 16 h / 20 °C

5.1: DIPEA / methanol

6.1: 100 percent / H₂ / Pd-C / methanol / 0.75 h / 20 °C

7.1: 0.425 g / EDC; HOAt; DMAP / dimethylformamide / 16 h / 20 °C

8.1: 100 percent / LiOH / tetrahydrofuran; H₂O / 12 h / 20 °C

9.1: 0.100 g / EDC / 24 h / 20 °C

With dmap; lithium hydroxide; thionyl chloride; 1-hydroxy-7-aza-benzotriazole; hydroxylamine hydrochloride; hydrogen; sodium hydrogencarbonate; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; palladium on activated charcoal; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide;

DOI:10.1039/b703116e

Reference yield:

N2-[(benzyloxy)carbonyl]-L-lysine (2212-75-1) → C55H79N5O11 (945496-86-6)

Guidance literature:

Multi-step reaction with 11 steps

1.1: KOH; 3 Angstroem molecular sieves / methanol / 16 h / 20 °C

2.1: m-CPBA / methanol / 2 h / 0 °C

3.1: TFA / CH₂Cl₂ / 1 h / 20 °C

3.2: 4.50 g / benzaldehyde / ethyl acetate / 0 - 20 °C

4.1: hydroxylamine hydrochloride / methanol / 0.33 h / 60 °C

5.1: SOCl₂ / 16 h / 0 - 20 °C

6.1: 2.89 g / NaHCO₃ / CH₂Cl₂ / 16 h / 20 °C

7.1: DIPEA / methanol

8.1: 100 percent / H₂ / Pd-C / methanol / 0.75 h / 20 °C

9.1: 0.425 g / EDC; HOAt; DMAP / dimethylformamide / 16 h / 20 °C

10.1: 100 percent / LiOH / tetrahydrofuran; H₂O / 12 h / 20 °C

11.1: 0.100 g / EDC / 24 h / 20 °C

With dmap; potassium hydroxide; lithium hydroxide; thionyl chloride; 1-hydroxy-7-aza-benzotriazole; 3 A molecular sieve; hydroxylamine hydrochloride; hydrogen; sodium hydrogencarbonate; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; N-ethyl-N,N-diisopropylamine; 3-chloro-benzenecarboperoxoic acid; trifluoroacetic acid; palladium on activated charcoal; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide;

DOI:10.1039/b703116e

upstream raw materials:

C₁₀H₁₈N₂O₄

C₄₅H₆₃N₃O₈

C₄₆H₆₅N₃O₈

C₂₁H₂₄N₂O₅