4-isopropylamino-2-(4-(3-(4-methylpiperazin-1-yl)propylamino)phenylamino)-5-aminopyrimidine

Base Information

Chemical Name:4-isopropylamino-2-(4-(3-(4-methylpiperazin-1-yl)propylamino)phenylamino)-5-aminopyrimidine
CAS No.:1350545-73-1
Molecular Formula:C₂₁H₃₄N₈
Molecular Weight:398.555
Hs Code.:

Synonyms:4-isopropylamino-2-(4-(3-(4-methylpiperazin-1-yl)propylamino)phenylamino)-5-aminopyrimidine

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Chemical Property of 4-isopropylamino-2-(4-(3-(4-methylpiperazin-1-yl)propylamino)phenylamino)-5-aminopyrimidine

Chemical Property:

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Technology Process of 4-isopropylamino-2-(4-(3-(4-methylpiperazin-1-yl)propylamino)phenylamino)-5-aminopyrimidine

There total 2 articles about 4-isopropylamino-2-(4-(3-(4-methylpiperazin-1-yl)propylamino)phenylamino)-5-aminopyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.9%

: 1350545-49-1
4-isopropylamino-2-(4-(3-(4-methylpiperazin-1-yl)propylamino)phenylamino)-5-nitropyrimidine

: 1350545-73-1
4-isopropylamino-2-(4-(3-(4-methylpiperazin-1-yl)propylamino)phenylamino)-5-aminopyrimidine

Guidance literature:: With iron; ammonium chloride; In ethanol; water; at 90 ℃; for 1.5h;

Reference yield:

: 890094-38-9
2-chloro-N-isopropyl-5-nitropyrimidin-4-amine

: 1350545-73-1
4-isopropylamino-2-(4-(3-(4-methylpiperazin-1-yl)propylamino)phenylamino)-5-aminopyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: butan-1-ol / 4 h / 90 °C

2: ammonium chloride; iron / water; ethanol / 1.5 h / 90 °C

With iron; ammonium chloride; In ethanol; water; butan-1-ol;

Reference yield: 69.1%

: 1350545-73-1
4-isopropylamino-2-(4-(3-(4-methylpiperazin-1-yl)propylamino)phenylamino)-5-aminopyrimidine

: 103-72-0
phenyl isothiocyanate

: 1350545-05-9
9-isopropylamino-2-(4-(3-(4-methylpiperazin-1-yl)propylamino)phenylamino)-8-phenylamino-9H-purine

Guidance literature:: With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 10.5h; Reflux;