ethyl 6-bromo-1-(2',3',5'-tri-O-benzoyl-β-D-ribofuranosyl)-4-quinolone-3-carboxylate

Base Information

Chemical Name:ethyl 6-bromo-1-(2',3',5'-tri-O-benzoyl-β-D-ribofuranosyl)-4-quinolone-3-carboxylate
CAS No.:224175-70-6
Molecular Formula:C₃₈H₃₀BrNO₁₀
Molecular Weight:740.561
Hs Code.:

Synonyms:ethyl 6-bromo-1-(2',3',5'-tri-O-benzoyl-β-D-ribofuranosyl)-4-quinolone-3-carboxylate

Suppliers and Price of ethyl 6-bromo-1-(2',3',5'-tri-O-benzoyl-β-D-ribofuranosyl)-4-quinolone-3-carboxylate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 2 raw suppliers

Chemical Property of ethyl 6-bromo-1-(2',3',5'-tri-O-benzoyl-β-D-ribofuranosyl)-4-quinolone-3-carboxylate

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

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Technology Process of ethyl 6-bromo-1-(2',3',5'-tri-O-benzoyl-β-D-ribofuranosyl)-4-quinolone-3-carboxylate

There total 4 articles about ethyl 6-bromo-1-(2',3',5'-tri-O-benzoyl-β-D-ribofuranosyl)-4-quinolone-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 6974-32-9
1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose

: 79607-23-1,122794-99-4
ethyl 6-bromo-4-oxo-1,4-dihydro-quinoline-3-carboxylate

: 224175-70-6
ethyl 6-bromo-1-(2',3',5'-tri-O-benzoyl-β-D-ribofuranosyl)-4-quinolone-3-carboxylate

Guidance literature:: 1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose; ethyl 6-bromo-4-oxo-1,4-dihydro-quinoline-3-carboxylate; With N,O-bis-(trimethylsilyl)-acetamide; In acetonitrile; at 80 ℃; for 0.5h; Inert atmosphere;

With trimethylsilyl trifluoromethanesulfonate; In acetonitrile; at 80 ℃; for 3h; Inert atmosphere;
DOI:10.1002/ardp.201300232

Reference yield:

: C₁₅H₁₈BrNO₃Si

: 67525-66-0
1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose

: 224175-70-6
ethyl 6-bromo-1-(2',3',5'-tri-O-benzoyl-β-D-ribofuranosyl)-4-quinolone-3-carboxylate

Guidance literature:: C₁₅H₁₈BrNO₃Si; 1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose; With trimethylsilyl trifluoromethanesulfonate; In acetonitrile; at 20 ℃; for 4h;

With sodium hydrogencarbonate; In water; acetonitrile; Cooling with ice;
DOI:10.1016/j.bmcl.2013.06.029

Reference yield:

: 83467-66-7
1-O-acetyl-2,3,5-tri-O-benzoyl-b-D-ribofuranose

: 79607-23-1,122794-99-4
ethyl 6-bromo-4-oxo-1,4-dihydro-quinoline-3-carboxylate

: 224175-70-6
ethyl 6-bromo-1-(2',3',5'-tri-O-benzoyl-β-D-ribofuranosyl)-4-quinolone-3-carboxylate

Guidance literature:: ethyl 6-bromo-4-oxo-1,4-dihydro-quinoline-3-carboxylate; With chloro-trimethyl-silane; N,O-Bis(trimethylsilyl)trifluoroacetamide; In acetonitrile; at 70 ℃; for 3h; Inert atmosphere;

1-O-acetyl-2,3,5-tri-O-benzoyl-b-D-ribofuranose; With trimethylsilyl trifluoromethanesulfonate; In acetonitrile; at 20 ℃; for 4h;
DOI:10.1039/c5ra11070j