(4Z,7Z,10Z,13Z,16Z,19Z)-N-(2-(2-(2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanamido)ethoxy)ethyl)docosa-4,7,10,13,16,19-hexaenamide

Base Information

Chemical Name:(4Z,7Z,10Z,13Z,16Z,19Z)-N-(2-(2-(2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanamido)ethoxy)ethyl)docosa-4,7,10,13,16,19-hexaenamide
CAS No.:1286173-95-2
Molecular Formula:C₄₃H₅₅ClN₂O₅
Molecular Weight:715.373
Hs Code.:

Synonyms:(4Z,7Z,10Z,13Z,16Z,19Z)-N-(2-(2-(2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanamido)ethoxy)ethyl)docosa-4,7,10,13,16,19-hexaenamide

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Chemical Property of (4Z,7Z,10Z,13Z,16Z,19Z)-N-(2-(2-(2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanamido)ethoxy)ethyl)docosa-4,7,10,13,16,19-hexaenamide

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Technology Process of (4Z,7Z,10Z,13Z,16Z,19Z)-N-(2-(2-(2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanamido)ethoxy)ethyl)docosa-4,7,10,13,16,19-hexaenamide

There total 2 articles about (4Z,7Z,10Z,13Z,16Z,19Z)-N-(2-(2-(2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanamido)ethoxy)ethyl)docosa-4,7,10,13,16,19-hexaenamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 6217-54-5
docosahexaenoic acid

: 1286173-98-5
N-(2-(2-aminoethoxy)ethyl)-2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanamide hydrochloride

: 1286173-95-2
(4Z,7Z,10Z,13Z,16Z,19Z)-N-(2-(2-(2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanamido)ethoxy)ethyl)docosa-4,7,10,13,16,19-hexaenamide

Guidance literature:: With N-ethyl-N,N-diisopropylamine; HATU; In acetonitrile; at 20 ℃; for 2h;

Reference yield:

: 1286173-97-4
tert-butyl 2-(2-(2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanamido)ethoxy)ethylcarbamate

: 1286173-95-2
(4Z,7Z,10Z,13Z,16Z,19Z)-N-(2-(2-(2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanamido)ethoxy)ethyl)docosa-4,7,10,13,16,19-hexaenamide

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride / 1,4-dioxane / 0.5 h / 20 °C

2: N-ethyl-N,N-diisopropylamine; HATU / acetonitrile / 2 h / 20 °C

With hydrogenchloride; N-ethyl-N,N-diisopropylamine; HATU; In 1,4-dioxane; acetonitrile;