3-Chloro-4-nitrophenylacetic acid

Base Information

Chemical Name:3-Chloro-4-nitrophenylacetic acid
CAS No.:163395-25-3
Molecular Formula:C8H6 Cl N O4
Molecular Weight:215.593
Hs Code.:
European Community (EC) Number:871-520-0
Mol file:163395-25-3.mol

Synonyms:163395-25-3;2-(3-chloro-4-nitrophenyl)acetic acid;3-CHLORO-4-NITROPHENYLACETIC ACID;BENZENEACETIC ACID,3-CHLORO-4-NITRO-;SCHEMBL1857263;3-Chloro-4-nitrobenzeneacetic acid;EN300-1981750

Suppliers and Price of 3-Chloro-4-nitrophenylacetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 3-Chloro-4-nitrophenylacetic acid

Chemical Property:

Vapor Pressure:3.6E-07mmHg at 25°C
Refractive Index:1.61
Boiling Point:401.6°C at 760 mmHg
PKA:3.68±0.10(Predicted)
Flash Point:196.7°C
PSA：83.12000
Density:1.532g/cm³
LogP:2.39850
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:214.9985354
Heavy Atom Count:14
Complexity:240

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:C

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1CC(=O)O)Cl)[N+](=O)[O-]

Technology Process of 3-Chloro-4-nitrophenylacetic acid

There total 2 articles about 3-Chloro-4-nitrophenylacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 53088-68-9
methyl 3-chlorophenylacetate

: 163395-25-3
3-chloro-4-nitrophenylacetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 38 percent / HNO₃, H₂SO₄ / 2 h / 0 °C

2: 6 N HCl / Heating

With hydrogenchloride; sulfuric acid; nitric acid;
DOI:10.1021/jo00125a026

Reference yield:

: 97522-06-0
methyl (3-chloro-4-nitrophenyl)acetate

: 163395-25-3
3-chloro-4-nitrophenylacetic acid

Guidance literature:: With hydrogenchloride; Heating;
DOI:10.1021/jo00125a026

Reference yield:

: 2-Amino-N-(3-hydroxy-benzyl)-acetamide; compound with trifluoro-acetic acid

: 163395-25-3
3-chloro-4-nitrophenylacetic acid

: 163395-23-1
2-(3-Chloro-4-nitro-phenyl)-N-[(3-hydroxy-benzylcarbamoyl)-methyl]-acetamide

Guidance literature:: With N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; triethylamine; In dichloromethane; N,N-dimethyl-formamide; 1.) room temperature, 30 min, 2.) 0 deg C, 4 h;
DOI:10.1021/jo00125a026