1-Boc-4-(4-bromo-phenyl)-piperidin-4-ol

Base Information

Chemical Name:1-Boc-4-(4-bromo-phenyl)-piperidin-4-ol
CAS No.:163209-96-9
Molecular Formula:C16H22BrNO3
Molecular Weight:356.26
Hs Code.:2933399090
DSSTox Substance ID:DTXSID40593289
Wikidata:Q82487739
Mol file:163209-96-9.mol

Synonyms:163209-96-9;1-boc-4-(4-bromo-phenyl)-piperidin-4-ol;1-boc-4-(4-bromophenyl)-4-hydroxypiperidine;TERT-BUTYL 4-(4-BROMOPHENYL)-4-HYDROXYPIPERIDINE-1-CARBOXYLATE;1-Boc-4-(4-bromophenyl)piperidin-4-ol;1-Piperidinecarboxylic acid, 4-(4-bromophenyl)-4-hydroxy-, 1,1-dimethylethyl ester;4-(4-bromo-phenyl)-4-hydroxy-piperidine-1-carboxylic acid tert-butyl ester;MFCD08689589;SCHEMBL1199600;DTXSID40593289;ZXVYIHCSSJUVBB-UHFFFAOYSA-N;AKOS016014946;AB48289;AC-9192;4-(4-Bromophenyl)-1-Boc-4-piperidinol;AS-33686;DA-21144;SY238832;CS-0007036;1-n-boc-4-(4-bromophenyl)-4-hydroxypiperidine;4-(N-BOC-4-Hydroxypiperidin-4-yl)bromobenzene;EN300-7424213;A810453;t-butyl 4-(4-bromophenyl)-4-hydroxypiperidine-1-carboxylate;tert-butyl 4-(4-bromophenyl)-4-oxidanyl-piperidine-1-carboxylate;4-(4-bromophenyl)-4-hydroxy-1-piperidinecarboxylic acid tert-butyl ester;4-(4-bromophenyl)-4-hydroxypiperidine-1-carboxylic acid tert-butyl ester

Suppliers and Price of 1-Boc-4-(4-bromo-phenyl)-piperidin-4-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
1-BOC-4-(4-BROMO-PHENYL)-PIPERIDIN-4-OL 95
20g
$ 3648.00

Crysdot
1-boc-4-(4-bromo-phenyl)-piperidin-4-ol 97%
5g
$ 715.00

Crysdot
1-boc-4-(4-bromo-phenyl)-piperidin-4-ol 97%
1g
$ 268.00

ChemScene
tert-butyl4-(4-bromophenyl)-4-hydroxypiperidine-1-carboxylate
1g
$ 283.00

ChemScene
tert-butyl4-(4-bromophenyl)-4-hydroxypiperidine-1-carboxylate
10g
$ 1281.00

ChemScene
tert-butyl4-(4-bromophenyl)-4-hydroxypiperidine-1-carboxylate
5g
$ 879.00

Chemenu
tert-butyl4-(4-bromophenyl)-4-hydroxypiperidine-1-carboxylate 95+%
5g
$ 795.00

American Custom Chemicals Corporation
1-BOC-4-(4-BROMO-PHENYL)-PIPERIDIN-4-OL 95.00%
1G
$ 432.60

Alichem
1-Boc-4-(4-Bromophenyl)-4-hydroxypiperidine
5g
$ 841.50

Alichem
1-Boc-4-(4-Bromophenyl)-4-hydroxypiperidine
1g
$ 224.72

Total 12 raw suppliers

Chemical Property of 1-Boc-4-(4-bromo-phenyl)-piperidin-4-ol

Chemical Property:

Vapor Pressure:1.9E-08mmHg at 25°C
Refractive Index:1.566
Boiling Point:438.1 °C at 760 mmHg
PKA:13.79±0.20(Predicted)
Flash Point:218.7 °C
PSA：49.77000
Density:1.367 g/cm³
LogP:3.60550
XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:355.07831
Heavy Atom Count:21
Complexity:364

Purity/Quality:

97% ^*data from raw suppliers

1-BOC-4-(4-BROMO-PHENYL)-PIPERIDIN-4-OL 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CCC(CC1)(C2=CC=C(C=C2)Br)O

Technology Process of 1-Boc-4-(4-bromo-phenyl)-piperidin-4-ol

There total 7 articles about 1-Boc-4-(4-bromo-phenyl)-piperidin-4-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 57988-58-6
4-(4-bromophenyl)-4-hydroxy-piperidine

: 163209-96-9
tert-butyl 4-(4-bromophenyl)-4-hydroxypiperidine-1-carboxylate

Guidance literature:: In methanol;
DOI:10.1016/j.bmcl.2006.04.061

Reference yield: 91.0%

: 589-87-7
1,4-bromoiodobenzene

: 79099-07-3
N-tert-butyloxycarbonylpiperidin-4-one

: 163209-96-9
tert-butyl 4-(4-bromophenyl)-4-hydroxypiperidine-1-carboxylate

Guidance literature:: 1,4-bromoiodobenzene; With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 2.5h; Inert atmosphere;

N-tert-butyloxycarbonylpiperidin-4-one; In tetrahydrofuran; at -78 ℃; for 0.5h; Inert atmosphere;
DOI:10.1021/ml300335r

Reference yield: 80.0%

: 106-37-6
1.4-dibromobenzene

: 79099-07-3
N-tert-butyloxycarbonylpiperidin-4-one

: 163209-96-9
tert-butyl 4-(4-bromophenyl)-4-hydroxypiperidine-1-carboxylate

Guidance literature:: 1.4-dibromobenzene; With n-butyllithium; In tetrahydrofuran; hexane; at -78 - -20 ℃; for 1h;

N-tert-butyloxycarbonylpiperidin-4-one; In tetrahydrofuran; hexane; at -78 ℃; for 1h;