Butanedioic acid, 2-cyano-3-(2-oxoethyl)-, dimethyl ester (9CI)

Base Information

• Chemical Name: Butanedioic acid, 2-cyano-3-(2-oxoethyl)-, dimethyl ester (9CI)
• CAS No.: 162956-90-3
• Molecular Formula: C₉H₁₁NO₅
• Molecular Weight: 213.19
• Mol file: 162956-90-3.mol

Synonyms:Butanedioicacid, 2-cyano-3-(2-oxoethyl)-, dimethyl ester (9CI)

Chemical Property of Butanedioic acid, 2-cyano-3-(2-oxoethyl)-, dimethyl ester (9CI)

Chemical Property:

• PSA: 0.00000
• LogP: 0.00000

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Butanedioic acid, 2-cyano-3-(2-oxoethyl)-, dimethyl ester (9CI)

There total 4 articles about Butanedioic acid, 2-cyano-3-(2-oxoethyl)-, dimethyl ester (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

dimethyl 2-cyanofumarate (54797-29-4) → 4-Cyano-3,4-dicarbomethoxybutanal (162956-90-3)

Guidance literature:

Multi-step reaction with 2 steps

1: acetonitrile / Heating

2: H₂O

With water; In acetonitrile;

DOI:10.1021/jo00097a054

Reference yield:

tert-butyldimethylsilyl vinyl ether (66031-93-4) + dimethyl 2-cyanofumarate (54797-29-4) → 4-Cyano-3,4-dicarbomethoxybutanal (162956-90-3) + (1S,2S)-4-(tert-Butyl-dimethyl-silanyloxy)-1-cyano-cyclobutane-1,2-dicarboxylic acid dimethyl ester

Guidance literature:

With zinc(II) chloride; In various solvent(s); Ambient temperature;

DOI:10.1021/jo00097a054

Reference yield:

1,2-Dicarbomethoxy-2-cyano-3-isobutoxycyclobutane → 4-Cyano-3,4-dicarbomethoxybutanal (162956-90-3)

Guidance literature:

With water;

DOI:10.1021/jo00097a054

upstream raw materials:

tert-butyldimethylsilyl vinyl ether

dimethyl 2-cyanofumarate