N-[3-(1H-tetrazol-5-yl)phenyl]-2-{1-[4-hydroxy-5-(5,6,7,8-tetrahydronaphthalen-2-yl)thiophen-3-yl]ethylidene}hydrazinecarbothioamide

Base Information

Chemical Name:N-[3-(1H-tetrazol-5-yl)phenyl]-2-{1-[4-hydroxy-5-(5,6,7,8-tetrahydronaphthalen-2-yl)thiophen-3-yl]ethylidene}hydrazinecarbothioamide
CAS No.:1294518-86-7
Molecular Formula:C₂₄H₂₃N₇OS₂
Molecular Weight:489.625
Hs Code.:

Synonyms:N-[3-(1H-tetrazol-5-yl)phenyl]-2-{1-[4-hydroxy-5-(5,6,7,8-tetrahydronaphthalen-2-yl)thiophen-3-yl]ethylidene}hydrazinecarbothioamide

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Chemical Property of N-[3-(1H-tetrazol-5-yl)phenyl]-2-{1-[4-hydroxy-5-(5,6,7,8-tetrahydronaphthalen-2-yl)thiophen-3-yl]ethylidene}hydrazinecarbothioamide

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Technology Process of N-[3-(1H-tetrazol-5-yl)phenyl]-2-{1-[4-hydroxy-5-(5,6,7,8-tetrahydronaphthalen-2-yl)thiophen-3-yl]ethylidene}hydrazinecarbothioamide

There total 2 articles about N-[3-(1H-tetrazol-5-yl)phenyl]-2-{1-[4-hydroxy-5-(5,6,7,8-tetrahydronaphthalen-2-yl)thiophen-3-yl]ethylidene}hydrazinecarbothioamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1294519-11-1
5-(3-isothiocyanatophenyl)-1H-tetrazole

: 1294519-01-9
4-(1-hydrazonoethyl)-2-(5,6,7,8-tetrahydronaphthalen-2-yl)thiophen-3-ol

: 1294518-86-7
N-[3-(1H-tetrazol-5-yl)phenyl]-2-{1-[4-hydroxy-5-(5,6,7,8-tetrahydronaphthalen-2-yl)thiophen-3-yl]ethylidene}hydrazinecarbothioamide

Guidance literature:: In N,N-dimethyl-formamide; at 20 ℃; for 48h;

Reference yield:

: 73732-51-1
5-(3-aminophenyl)-1H-tetrazole

: 1294518-86-7
N-[3-(1H-tetrazol-5-yl)phenyl]-2-{1-[4-hydroxy-5-(5,6,7,8-tetrahydronaphthalen-2-yl)thiophen-3-yl]ethylidene}hydrazinecarbothioamide

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / dichloromethane; N,N-dimethyl-formamide; water / 1 h / 0 °C

2: N,N-dimethyl-formamide / 48 h / 20 °C

With triethylamine; In dichloromethane; water; N,N-dimethyl-formamide;