Technology Process of 2-Pyridinemethanamine,6-ethyl-N-methyl-(9CI)
There total 8 articles about 2-Pyridinemethanamine,6-ethyl-N-methyl-(9CI) which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogen;
palladium on activated charcoal;
In
methanol;
for 4h;
under 3040 Torr;
Yield given;
DOI:10.1021/jm970636+
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 5.5 g / Et3N / diethyl ether / 3 h
2: 1.) oxalyl chloride, DMSO, 2.) Et3N / 1.) CH2Cl2, 20 min, 2.) CH2Cl2, 20 min
3: 48 percent / H2, 48 percent HBF4 / Raney Ni / ethanol / 6 h / 760 Torr
4: 870 mg / LiAlH4 / tetrahydrofuran / 1 h / 0 °C
5: 1.) oxalyl chloride, DMSO, 2.) Et3N / 1.) CH2Cl2, 20 min, 2.) CH2Cl2, 20 min
6: methanol / 16 h
7: H2 / 10 percent Pd/C / methanol / 4 h / 3040 Torr
With
lithium aluminium tetrahydride; tetrafluoroboric acid; oxalyl dichloride; hydrogen; dimethyl sulfoxide; triethylamine;
palladium on activated charcoal; nickel;
In
tetrahydrofuran; methanol; diethyl ether; ethanol;
DOI:10.1021/jm970636+
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 1.) oxalyl chloride, DMSO, 2.) Et3N / 1.) CH2Cl2, 20 min, 2.) CH2Cl2, 20 min
2: 48 percent / H2, 48 percent HBF4 / Raney Ni / ethanol / 6 h / 760 Torr
3: 870 mg / LiAlH4 / tetrahydrofuran / 1 h / 0 °C
4: 1.) oxalyl chloride, DMSO, 2.) Et3N / 1.) CH2Cl2, 20 min, 2.) CH2Cl2, 20 min
5: methanol / 16 h
6: H2 / 10 percent Pd/C / methanol / 4 h / 3040 Torr
With
lithium aluminium tetrahydride; tetrafluoroboric acid; oxalyl dichloride; hydrogen; dimethyl sulfoxide; triethylamine;
palladium on activated charcoal; nickel;
In
tetrahydrofuran; methanol; ethanol;
DOI:10.1021/jm970636+