5-(4-chlorophenyl)-1,3,5,7,9,10-hexahydropyrimido[5',4'-5,6]pyridine[2,3-d]pyrimidine-2,4,6,8-tetraone

Base Information

• Chemical Name: 5-(4-chlorophenyl)-1,3,5,7,9,10-hexahydropyrimido[5',4'-5,6]pyridine[2,3-d]pyrimidine-2,4,6,8-tetraone
• CAS No.: 1207379-34-7
• Molecular Formula: C₁₅H₁₀ClN₅O₄
• Molecular Weight: 359.728
• Mol file: 1207379-34-7.mol

Synonyms:5-(4-chlorophenyl)-1,3,5,7,9,10-hexahydropyrimido[5',4'-5,6]pyridine[2,3-d]pyrimidine-2,4,6,8-tetraone

Chemical Property of 5-(4-chlorophenyl)-1,3,5,7,9,10-hexahydropyrimido[5',4'-5,6]pyridine[2,3-d]pyrimidine-2,4,6,8-tetraone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-(4-chlorophenyl)-1,3,5,7,9,10-hexahydropyrimido[5',4'-5,6]pyridine[2,3-d]pyrimidine-2,4,6,8-tetraone

There total 3 articles about 5-(4-chlorophenyl)-1,3,5,7,9,10-hexahydropyrimido[5',4'-5,6]pyridine[2,3-d]pyrimidine-2,4,6,8-tetraone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

4-Amino-2,6-dihydroxypyrimidine (873-83-6) + BARBITURIC ACID (67-52-7,944357-77-1) + 4-chlorobenzaldehyde (104-88-1) → 5-(4-chlorophenyl)-1,3,5,7,9,10-hexahydropyrimido[5',4'-5,6]pyridine[2,3-d]pyrimidine-2,4,6,8-tetraone (1207379-34-7)

Guidance literature:

With hexamethylenetetramine-based ionic liquid immobilized on the MIL-101(Cr) metal-organic framework; In neat (no solvent); at 80 ℃; for 0.166667h; Reagent/catalyst; Temperature; Catalytic behavior;

DOI:10.1039/d0ra09054a

Reference yield: 96.0%

BARBITURIC ACID (67-52-7,944357-77-1) + 4-chlorobenzaldehyde (104-88-1) → 5-(4-chlorophenyl)-1,3,5,7,9,10-hexahydropyrimido[5',4'-5,6]pyridine[2,3-d]pyrimidine-2,4,6,8-tetraone (1207379-34-7)

Guidance literature:

With ammonium acetate; In ethanol; at 50 ℃; for 0.2h;

DOI:10.1002/jccs.201800120

Reference yield: 96.0%

4-Amino-2,6-dihydroxypyrimidine (873-83-6) + 4-chlorobenzaldehyde (104-88-1) → 5-(4-chlorophenyl)-1,3,5,7,9,10-hexahydropyrimido[5',4'-5,6]pyridine[2,3-d]pyrimidine-2,4,6,8-tetraone (1207379-34-7)

Guidance literature:

With SBA-15 supported sulfonic acid nanocatalyst; In neat (no solvent); at 120 ℃; for 0.166667h;

DOI:10.1007/s13738-015-0604-1

upstream raw materials:

4-Amino-2,6-dihydroxypyrimidine

BARBITURIC ACID

4-chlorobenzaldehyde