1-(3-(trifluoromethyl)benzyl)-4-(1-(4-methoxybenzyl)-5-amino-1H-imidazol-4-yl)-5-imino-1H-imidazol-2(5H)-one

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Chemical Name:1-(3-(trifluoromethyl)benzyl)-4-(1-(4-methoxybenzyl)-5-amino-1H-imidazol-4-yl)-5-imino-1H-imidazol-2(5H)-one
CAS No.:1421053-98-6
Molecular Formula:C₂₂H₁₉F₃N₆O₂
Molecular Weight:456.427
Hs Code.:

Synonyms:1-(3-(trifluoromethyl)benzyl)-4-(1-(4-methoxybenzyl)-5-amino-1H-imidazol-4-yl)-5-imino-1H-imidazol-2(5H)-one

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Chemical Property of 1-(3-(trifluoromethyl)benzyl)-4-(1-(4-methoxybenzyl)-5-amino-1H-imidazol-4-yl)-5-imino-1H-imidazol-2(5H)-one

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Technology Process of 1-(3-(trifluoromethyl)benzyl)-4-(1-(4-methoxybenzyl)-5-amino-1H-imidazol-4-yl)-5-imino-1H-imidazol-2(5H)-one

There total 4 articles about 1-(3-(trifluoromethyl)benzyl)-4-(1-(4-methoxybenzyl)-5-amino-1H-imidazol-4-yl)-5-imino-1H-imidazol-2(5H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₂H₁₉F₃N₆O₂

: 1421053-98-6
1-(3-(trifluoromethyl)benzyl)-4-(1-(4-methoxybenzyl)-5-amino-1H-imidazol-4-yl)-5-imino-1H-imidazol-2(5H)-one

Guidance literature:: With 1,8-diazabicyclo[5.4.0]undec-7-ene; In acetonitrile; at 20 ℃; for 2h; Inert atmosphere;
DOI:10.1016/j.bmc.2012.11.050

Reference yield:

: 1421053-51-1
C₁₃H₁₃N₅O

: 1421053-98-6
1-(3-(trifluoromethyl)benzyl)-4-(1-(4-methoxybenzyl)-5-amino-1H-imidazol-4-yl)-5-imino-1H-imidazol-2(5H)-one

Guidance literature:: Multi-step reaction with 3 steps

1: 1,8-diazabicyclo[5.4.0]undec-7-ene / ethanol / 3 h / 20 °C

2: acetonitrile / 3 h / 20 °C / Inert atmosphere

3: 1,8-diazabicyclo[5.4.0]undec-7-ene / acetonitrile / 2 h / 20 °C / Inert atmosphere

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In ethanol; acetonitrile;
DOI:10.1016/j.bmc.2012.11.050

Reference yield:

: 52794-59-9
3-(trifluoromethyl)phenylmethyl isocyanate

: 1421053-98-6
1-(3-(trifluoromethyl)benzyl)-4-(1-(4-methoxybenzyl)-5-amino-1H-imidazol-4-yl)-5-imino-1H-imidazol-2(5H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: acetonitrile / 3 h / 20 °C / Inert atmosphere

2: 1,8-diazabicyclo[5.4.0]undec-7-ene / acetonitrile / 2 h / 20 °C / Inert atmosphere

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In acetonitrile;
DOI:10.1016/j.bmc.2012.11.050