1-Propanone,1-(3-amino-4-pyridinyl)-(9CI)

Base Information

• Chemical Name: 1-Propanone,1-(3-amino-4-pyridinyl)-(9CI)
• CAS No.: 161872-00-0
• Molecular Formula: C₈H₁₀N₂O
• Molecular Weight: 150.18
• Mol file: 161872-00-0.mol

Synonyms:1-Propanone,1-(3-amino-4-pyridinyl)-(9CI)

Chemical Property of 1-Propanone,1-(3-amino-4-pyridinyl)-(9CI)

Chemical Property:

• Boiling Point: 318.7±22.0 °C(Predicted)
• PKA: 3.65±0.36(Predicted)
• PSA: 55.98000
• Density: 1.129±0.06 g/cm3(Predicted)
• LogP: 1.83770

Purity/Quality:

97% ^*data from raw suppliers

1-(3-Aminopyridin-4-yl)propan-1-one 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Propanone,1-(3-amino-4-pyridinyl)-(9CI)

There total 1 articles about 1-Propanone,1-(3-amino-4-pyridinyl)-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(3-Nitro-pyridin-4-yl)-propan-1-one → 3-amino-4-(1-oxopropyl)pyridine (161872-00-0)

Guidance literature:

With sodium dithionite; In ethanol; for 14h; Yield given; Heating;

DOI:10.1021/jm00007a008

Reference yield:

3-amino-4-(1-oxopropyl)pyridine (161872-00-0) → 5-amino-2-bromo-4-(1-oxopropyl)pyridine + 1-(3-Amino-2-bromo-pyridin-4-yl)-propan-1-one

Guidance literature:

With pyrrolidone hydrotribromide; sodium hydrogencarbonate; In tetrahydrofuran; for 4h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; Ambient temperature;

DOI:10.1021/jm00007a008

Refernces