1,4-Dioxaspiro[4.4]non-6-ene-6-carbaldehyde

Base Information

Chemical Name:1,4-Dioxaspiro[4.4]non-6-ene-6-carbaldehyde
CAS No.:161521-90-0
Molecular Formula:C₈H₁₀O₃
Molecular Weight:154.166
Hs Code.:
DSSTox Substance ID:DTXSID90498937
Mol file:161521-90-0.mol

Synonyms:161521-90-0;1,4-dioxaspiro[4.4]non-6-ene-6-carbaldehyde;1,4-Dioxaspiro[4.4]non-6-ene-6-carboxaldehyde (9CI);1,4-dioxaspiro[4.4]non-8-ene-9-carbaldehyde;DTXSID90498937

Suppliers and Price of 1,4-Dioxaspiro[4.4]non-6-ene-6-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1,4-Dioxaspiro[4.4]non-6-ene-6-carbaldehyde

Chemical Property:

Boiling Point:273.9±40.0 °C(Predicted)
PSA：35.53000
Density:1.21±0.1 g/cm3(Predicted)
LogP:0.64860
XLogP3:-0.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:154.062994177
Heavy Atom Count:11
Complexity:201

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2(C(=C1)C=O)OCCO2

Technology Process of 1,4-Dioxaspiro[4.4]non-6-ene-6-carbaldehyde

There total 1 articles about 1,4-Dioxaspiro[4.4]non-6-ene-6-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 80963-19-5
α-(hydroxymethyl)cyclopentenone ethylene ketal

: 161521-90-0
1,4-Dioxa-spiro[4.4]non-6-ene-6-carbaldehyde

Guidance literature:: With dipyridine chromium trioxide; In dichloromethane;
DOI:10.1246/cl.1994.2245

Reference yield:

: 161521-90-0
1,4-Dioxa-spiro[4.4]non-6-ene-6-carbaldehyde

: 161521-96-6
(E)-3-[5-(tert-Butyl-diphenyl-silanyloxy)-cyclopent-1-enyl]-acrylic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 64 percent / LiCl, DBU / acetonitrile

2: 100 percent / (COOH)2 / CH₂Cl₂; H₂O

3: 1.) NaBH₄, CeCl₃*7H₂O, 2.) imidazole, DMAP / 1.) MeOH, 2.) DMF

With 1H-imidazole; dmap; sodium tetrahydroborate; cerium(III) chloride; oxalic acid; 1,8-diazabicyclo[5.4.0]undec-7-ene; lithium chloride; In dichloromethane; water; acetonitrile;
DOI:10.1246/cl.1994.2245

Reference yield:

: 161521-90-0
1,4-Dioxa-spiro[4.4]non-6-ene-6-carbaldehyde

: (E)-3-[4-(tert-Butyl-diphenyl-silanyloxy)-2-methylene-hexahydro-pentalen-3a-yl]-acrylic acid methyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: 64 percent / LiCl, DBU / acetonitrile

2: 100 percent / (COOH)2 / CH₂Cl₂; H₂O

3: 1.) NaBH₄, CeCl₃*7H₂O, 2.) imidazole, DMAP / 1.) MeOH, 2.) DMF

4: 7 percent / palladium acetate, (i-Pr)3P, BuLi / tetrahydrofuran; hexane / 72 h / 60 °C

With 1H-imidazole; dmap; sodium tetrahydroborate; n-butyllithium; cerium(III) chloride; palladium diacetate; oxalic acid; 1,8-diazabicyclo[5.4.0]undec-7-ene; lithium chloride; tris(1-methylethyl)phosphine; In tetrahydrofuran; hexane; dichloromethane; water; acetonitrile;
DOI:10.1246/cl.1994.2245