(R)-methyl tetrahydro-2H-thiopyran-3-carboxylate

Base Information

Chemical Name:(R)-methyl tetrahydro-2H-thiopyran-3-carboxylate
CAS No.:161404-77-9
Molecular Formula:C₇H₁₂O₂S
Molecular Weight:160.237
Hs Code.:
DSSTox Substance ID:DTXSID101174827
Mol file:161404-77-9.mol

Synonyms:161404-77-9;methyl (3R)-thiane-3-carboxylate;2H-Thiopyran-3-carboxylicacid,tetrahydro-,methylester,(R)-(9CI);(R)-methyl tetrahydro-2H-thiopyran-3-carboxylate;DTXSID101174827;2H-Thiopyran-3-carboxylic acid, tetrahydro-, methyl ester, (R)-

Suppliers and Price of (R)-methyl tetrahydro-2H-thiopyran-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of (R)-methyl tetrahydro-2H-thiopyran-3-carboxylate

Chemical Property:

XLogP3:1.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:160.05580079
Heavy Atom Count:10
Complexity:125

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC(=O)C1CCCSC1
Isomeric SMILES:COC(=O)[C@H]1CCCSC1

Technology Process of (R)-methyl tetrahydro-2H-thiopyran-3-carboxylate

There total 2 articles about (R)-methyl tetrahydro-2H-thiopyran-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4-(Imidazole-1-carbothioyloxy)-tetrahydro-thiopyran-3-carboxylic acid methyl ester

: 161404-77-9
(3S)-Methyl tetrahydro-2H-thiopyran-3-carboxylate

: 161404-77-9
(3R)-Methyl tetrahydro-2H-thiopyran-3-carboxylate

Guidance literature:: With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In 1,4-dioxane; at 104 ℃; for 2.5h; Title compound not separated from byproducts;
DOI:10.1021/jo00124a042

Reference yield:

: 4-(Imidazole-1-carbothioyloxy)-tetrahydro-thiopyran-3-carboxylic acid methyl ester

: 161404-77-9
(3S)-Methyl tetrahydro-2H-thiopyran-3-carboxylate

: 161404-77-9
(3R)-Methyl tetrahydro-2H-thiopyran-3-carboxylate

Guidance literature:: With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In 1,4-dioxane; at 104 ℃; for 2.5h; Title compound not separated from byproducts;
DOI:10.1021/jo00124a042

Reference yield:

: 161404-77-9
Methyl tetrahydro-2H-thiopyran-3-carboxylate

: 161511-61-1
(S)-Tetrahydro-thiopyran-3-carboxylic acid

: 161511-61-1
(R)-Tetrahydro-thiopyran-3-carboxylic acid

Guidance literature:: With lithium hydroxide; In tetrahydrofuran; water; at 23 ℃; for 8h; Title compound not separated from byproducts;
DOI:10.1021/jo00124a042