2-amino-4-(3-nitrophenyl)-6-(phenylsulfanyl)-3,5-pyridinedicarbonitrile

Base Information

• Chemical Name: 2-amino-4-(3-nitrophenyl)-6-(phenylsulfanyl)-3,5-pyridinedicarbonitrile
• CAS No.: 1019060-90-2
• Molecular Formula: C₁₉H₁₁N₅O₂S
• Molecular Weight: 373.395
• Mol file: 1019060-90-2.mol

Synonyms:2-amino-4-(3-nitrophenyl)-6-(phenylsulfanyl)-3,5-pyridinedicarbonitrile

Chemical Property of 2-amino-4-(3-nitrophenyl)-6-(phenylsulfanyl)-3,5-pyridinedicarbonitrile

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-amino-4-(3-nitrophenyl)-6-(phenylsulfanyl)-3,5-pyridinedicarbonitrile

There total 5 articles about 2-amino-4-(3-nitrophenyl)-6-(phenylsulfanyl)-3,5-pyridinedicarbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

3-nitro-benzaldehyde (99-61-6) + thiophenol (108-98-5) + malononitrile (109-77-3) → 2-amino-4-(3-nitrophenyl)-6-(phenylsulfanyl)-3,5-pyridinedicarbonitrile (1019060-90-2)

Guidance literature:

With magnetic Co^II(macrocyclic Schiff base ligand) immobilized on Fe₃O₄ nanoparticles; In neat (no solvent); at 100 ℃; for 0.183333h;

DOI:10.1002/aoc.5769

Reference yield:

3-nitrobenzylidenemalononitrile (2826-32-6) + thiophenol (108-98-5) + malononitrile (109-77-3) → 2-amino-4-(3-nitrophenyl)-6-(phenylsulfanyl)-3,5-pyridinedicarbonitrile (1019060-90-2)

Guidance literature:

With copper(I) iodide; In ethanol; for 1.83333h; Reflux; Green chemistry;

DOI:10.1080/17415993.2012.728220

Reference yield:

3-nitro-benzaldehyde (99-61-6) → 2-amino-4-(3-nitrophenyl)-6-(phenylsulfanyl)-3,5-pyridinedicarbonitrile (1019060-90-2)

Guidance literature:

Multi-step reaction with 2 steps

1: ethanol / 0.25 h / 60 °C / Green chemistry

2: copper(I) iodide / ethanol / 1.83 h / Reflux; Green chemistry

With copper(I) iodide; In ethanol;

DOI:10.1080/17415993.2012.728220

upstream raw materials:

3-nitro-benzaldehyde

thiophenol

malononitrile

3-nitrobenzylidenemalononitrile