(E)-3-[5-((E)-2-Carboxy-vinyl)-2,4-bis-methylselanyl-phenyl]-acrylic acid

Base Information

• Chemical Name: (E)-3-[5-((E)-2-Carboxy-vinyl)-2,4-bis-methylselanyl-phenyl]-acrylic acid
• CAS No.: 133430-84-9
• Molecular Formula: C₁₄H₁₄O₄Se₂
• Molecular Weight: 404.183
• Mol file: 133430-84-9.mol

Synonyms:(E)-3-[5-((E)-2-Carboxy-vinyl)-2,4-bis-methylselanyl-phenyl]-acrylic acid

Chemical Property of (E)-3-[5-((E)-2-Carboxy-vinyl)-2,4-bis-methylselanyl-phenyl]-acrylic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-3-[5-((E)-2-Carboxy-vinyl)-2,4-bis-methylselanyl-phenyl]-acrylic acid

There total 5 articles about (E)-3-[5-((E)-2-Carboxy-vinyl)-2,4-bis-methylselanyl-phenyl]-acrylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

1,3-di(ethoxycarbonylvinyl)-4,6-dimethylselenobenzene (133430-81-6) → (E)-3-[5-((E)-2-Carboxy-vinyl)-2,4-bis-methylselanyl-phenyl]-acrylic acid (133430-84-9)

Guidance literature:

With potassium hydroxide; In ethanol;

Reference yield:

1,5-dibromo-2,4-dimethylbenzene (615-87-2) → (E)-3-[5-((E)-2-Carboxy-vinyl)-2,4-bis-methylselanyl-phenyl]-acrylic acid (133430-84-9)

Guidance literature:

Multi-step reaction with 5 steps

1: CrO₃ / acetic acid; H₂SO₄

2: aq.H₂SO₄ / ethanol

3: 1)K₂CO₃ / 1) DMF, 5 deg C 2) 12 h

4: 74 percent / 40percent NaOH, tetrabutylammonium iodide / CH₂Cl₂ / 1 h / Ambient temperature

5: 94 percent / aq. KOH / ethanol

With chromium(VI) oxide; potassium hydroxide; sodium hydroxide; sulfuric acid; tetra-(n-butyl)ammonium iodide; potassium carbonate; In ethanol; dichloromethane; sulfuric acid; acetic acid;

Reference yield:

2,4-dibromobenzene-1,5-dicarboxaldehyde (97094-37-6) → (E)-3-[5-((E)-2-Carboxy-vinyl)-2,4-bis-methylselanyl-phenyl]-acrylic acid (133430-84-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 1)K₂CO₃ / 1) DMF, 5 deg C 2) 12 h

2: 74 percent / 40percent NaOH, tetrabutylammonium iodide / CH₂Cl₂ / 1 h / Ambient temperature

3: 94 percent / aq. KOH / ethanol

With potassium hydroxide; sodium hydroxide; tetra-(n-butyl)ammonium iodide; potassium carbonate; In ethanol; dichloromethane;

upstream raw materials:

1,3-di(ethoxycarbonylvinyl)-4,6-dimethylselenobenzene

1,5-dibromo-2,4-dimethylbenzene

2,4-dibromobenzene-1,5-dicarboxaldehyde

4,6-dimethylselenoisophthalaldehyde