N-[4-({[4-(3-ethyl-7-morpholin-4-yl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-yl)phenyl]carbamoyl}amino)phenyl]-N₂,N₂-dimethylglycinamide

Base Information

• Chemical Name: N-[4-({[4-(3-ethyl-7-morpholin-4-yl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-yl)phenyl]carbamoyl}amino)phenyl]-N₂,N₂-dimethylglycinamide
• CAS No.: 1173207-53-8
• Molecular Formula: C₂₇H₃₂N₁₀O₃
• Molecular Weight: 544.616

Synonyms:N-[4-({[4-(3-ethyl-7-morpholin-4-yl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-yl)phenyl]carbamoyl}amino)phenyl]-N₂,N₂-dimethylglycinamide

Chemical Property of N-[4-({[4-(3-ethyl-7-morpholin-4-yl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-yl)phenyl]carbamoyl}amino)phenyl]-N₂,N₂-dimethylglycinamide

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Technology Process of N-[4-({[4-(3-ethyl-7-morpholin-4-yl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-yl)phenyl]carbamoyl}amino)phenyl]-N₂,N₂-dimethylglycinamide

There total 1 articles about N-[4-({[4-(3-ethyl-7-morpholin-4-yl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-yl)phenyl]carbamoyl}amino)phenyl]-N₂,N₂-dimethylglycinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

1-(4-aminophenyl)-3-[4-(3-ethyl-7-morpholin-4-yl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-yl)phenyl]urea (1173207-52-7) + N,N-dimethylaminoacetyl chloride hydrochloride (60853-81-8) → N-[4-({[4-(3-ethyl-7-morpholin-4-yl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-yl)phenyl]carbamoyl}amino)phenyl]-N2,N2-dimethylglycinamide (1173207-53-8)

Guidance literature:

1-(4-aminophenyl)-3-[4-(3-ethyl-7-morpholin-4-yl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-yl)phenyl]urea; With triethylamine; In chloroform; for 0.25h;

N,N-dimethylaminoacetyl chloride hydrochloride; With dmap; In chloroform;

upstream raw materials:

1-(4-aminophenyl)-3-[4-(3-ethyl-7-morpholin-4-yl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-yl)phenyl]urea

N,N-dimethylaminoacetyl chloride hydrochloride

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