1,2,3-triphenylcyclopropane

Base Information

• Chemical Name: 1,2,3-triphenylcyclopropane
• CAS No.: 19120-38-8
• Molecular Formula: C₂₁H₁₈
• Molecular Weight: 270.374
• Mol file: 19120-38-8.mol

Synonyms:1,2,3-triphenylcyclopropane

Chemical Property of 1,2,3-triphenylcyclopropane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,2,3-triphenylcyclopropane

There total 32 articles about 1,2,3-triphenylcyclopropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

(E)-1,2-diphenyl-ethene (103-30-0) → 1,2,3-triphenylcyclopropane (19120-38-8)

Guidance literature:

In dichloromethane; at -78 ℃;

DOI:10.1021/ja00546a039

Reference yield: 94.0%

(E)-1,2-diphenyl-ethene (103-30-0) + N'-benzylidene-2-nitrobenzenesulfonohydrazide (97025-65-5) → 1,2,3-triphenylcyclopropane (19120-38-8)

Guidance literature:

N'-benzylidene-2-nitrobenzenesulfonohydrazide; With sodium hydride; In dichloromethane; at 20 ℃; for 1h; Inert atmosphere; Sealed tube;

(E)-1,2-diphenyl-ethene; With silver trifluoromethanesulfonate; In dichloromethane; at 40 ℃; for 18h; Reagent/catalyst; Catalytic behavior; Inert atmosphere; Sealed tube;

DOI:10.1021/acs.orglett.7b03374

Reference yield: 84.0%

(E)-1,2-diphenyl-ethene (103-30-0) + 7-phenylcycloheptatriene (1541-11-3) → trans-1,2,3-triphenylcyclopropane (10539-10-3,795-11-9,19120-38-8)

Guidance literature:

With (acetonitrile)[2-di-tert-butyl(2′,4′,4′,6'-triisopropylbiphenyl)phosphine]gold(I) hexafluoroantimonate; In 1,2-dichloro-ethane; at 120 ℃; for 2.25h; stereoselective reaction; Inert atmosphere;

DOI:10.1021/ja205046h

upstream raw materials:

stilbene

<3-Chlor-1,2,3-triphenyl-propyl>-diphenyl-phosphinoxid

benzylidene dichloride

Benzyl phenyl sulfone

Downstream raw materials:

trans-4,5-Dihydro-3,4,5-triphenylisoxazole